Evidence map›Paper›PMID 30899092›Full record

ArticleMolecular psychiatry2021

The BDNF

Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez and 58 more

Abstract read
In one paragraph

Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Brain Topological Changes in Subjective Cognitive Decline and Associations with Amyloid Stages.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Multimodal spatial gradients to explain regional susceptibility to fibrillar tau in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. BDNF Val66Met moderates episodic memory decline and tau biomarker increases in early sporadic Alzheimer's disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

68 authors.

Nicolai FranzmeierInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.ORCID http://orcid.org/0000-0001-9736-2283
Jinyi RenInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Alexander DammInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Gemma Monté-RubioFundació ACE, Alzheimer Treatment and Research Center, Barcelona, Spain.
Mercè BoadaFundació ACE, Alzheimer Treatment and Research Center, Barcelona, Spain.
Agustín RuizFundació ACE, Alzheimer Treatment and Research Center, Barcelona, Spain.
Alfredo RamirezDepartment of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0003-4991-763X
Frank JessenDepartment of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.
Emrah DüzelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Octavio Rodríguez GómezFundació ACE, Alzheimer Treatment and Research Center, Barcelona, Spain.
Tammie BenzingerDepartment of Radiology, Washington University in St Louis, St Louis, MO, USA.
Alison GoateDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-0576-2472
Celeste M KarchKnight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-6854-5547
Anne M FaganKnight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
Eric McDadeDepartment of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
Katharina BuergerInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Johannes LevinGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Marco DueringInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Martin DichgansInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Marc Suárez-CalvetGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Christian HaassGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.ORCID http://orcid.org/0000-0002-4869-1627
Brian A GordonKnight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-2109-2955
Yen Ying LimThe Florey Institute, The University of Melbourne, Parkville, VIC, Australia.
Colin L MastersThe Florey Institute, The University of Melbourne, Parkville, VIC, Australia.
Daniel JanowitzInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Cihan CatakInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Steffen WolfsgruberDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Michael WagnerDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Esther MilzDepartment of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.
Sonia Moreno-GrauFundació ACE, Alzheimer Treatment and Research Center, Barcelona, Spain.
Stefan TeipelGerman Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Michel J GrotheGerman Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.ORCID http://orcid.org/0000-0003-2600-9022
Ingo KilimannGerman Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Martin RossorDementia Research Centre, University College London, Queen Square, London, UK.
Nick FoxDementia Research Centre, University College London, Queen Square, London, UK.
Christoph LaskeHertie Institute for Clinical Brain Research, Tübingen, Germany.
Jasmeer ChhatwalMassachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.
Robert PerneczkyGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.ORCID http://orcid.org/0000-0003-1981-7435
Jae-Hong LeeDepartment of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Annika SpottkeGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Henning BoeckerGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Frederic BrosseronDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Klaus FliessbachDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Michael T HenekaDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-4996-1630
Peter NestorGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Oliver PetersGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Manuel FuentesGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Felix MenneGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Josef PrillerGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Eike J SpruthGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Christiana FrankeGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Anja SchneiderDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Christine WesterteicherDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Oliver SpeckGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Jens WiltfangGerman Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.ORCID http://orcid.org/0000-0003-1492-5330
Claudia BartelsDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, University of Goettingen, Goettingen, Germany.
Miguel Ángel Araque CaballeroInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.
Coraline MetzgerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Daniel BittnerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Stephen SallowayDepartment of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID http://orcid.org/0000-0002-2631-0942
Adrian DanekDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID http://orcid.org/0000-0001-8857-5383
Jason HassenstabDepartment of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
Igor YakushevDepartment of Nuclear Medicine, Technical University of Munich, Munich, Germany.
Peter R SchofieldNeuroscience Research Australia, Barker Street Randwick, Sydney, NSW, 2031, Australia.ORCID http://orcid.org/0000-0003-2967-9662
John C MorrisKnight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
Randall J BatemanKnight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
Michael EwersInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany. michael.ewers@med.uni-muenchen.de.

Funding

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Imaging CoreU19AG032438 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2010 to 2025
$53.9M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI XIONG, CHENGJIE · 2005 to 2025
$49.5M
Dominantly Inherited Alzheimer NetworkUF1AG032438 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2014 to 2017
$21.6M
Democratising Machine Learning for researchers working in Alzheimer's spaceR01AG058676 · NIA · UNIVERSITY OF MELBOURNE · PI MASTERS, COLIN · 2018 to 2022
$10.9M
THE XNAT IMAGING INFORMATICS PLATFORMR01EB009352 · NIBIB · WASHINGTON UNIVERSITY · PI Daniel Scott Marcus · 2009 to 2026
$9.3M
proj 3 - NINDS INSTIUTIONAL CENTER CORE GRANTS TO SUPPORT NEUROSCIENCE RESEARP30NS048056 · NINDS · WASHINGTON UNIVERSITY · PI MARCUS, DANIEL SCOTT · 2004 to 2014
$7.4M
NINDS CENTER CORE FOR BRAIN IMAGINGP30NS098577 · NINDS · WASHINGTON UNIVERSITY · PI HERSHEY, TAMARA G, MARCUS, DANIEL SCOTT · 2016 to 2019
$2.4M
Age and genetic influence on fcMRI networks in autosomal dominant and sporadic ADK23AG049087 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI CHHATWAL, JASMEER P · 2015 to 2019
$931k
Neuroimaging Markers of Emerging Dysfunction In Preclinical Alzheimer DiseaseK01AG053474 · NIA · WASHINGTON UNIVERSITY · PI GORDON, BRIAN ANDREW · 2017 to 2021
$623k
Medical Research Council MR/009076/1Medical Research Council MR/L023784/1Medical Research Council MR/L023784/2NCATS NIH HHS UL1 TR002345NIA NIH HHS K01 AG053474NIA NIH HHS K23 AG049087NIA NIH HHS P01 AG026276NIA NIH HHS R01 AG058676NIA NIH HHS U19 AG032438NIA NIH HHS U24 AG021886NIA NIH HHS UF1 AG032438NIBIB NIH HHS R01 EB009352NINDS NIH HHS P30 NS048056NINDS NIH HHS P30 NS098577
6 · The paper itself

Abstract

In Alzheimer's disease (AD), a single-nucleotide polymorphism in the gene encoding brain-derived neurotrophic factor (BDNF

Indexed as

Alzheimer DiseaseCognitive DysfunctionAgedAmyloid beta-PeptidesBrainBrain-Derived Neurotrophic FactorHippocampusHumansMagnetic Resonance ImagingPolymorphism, Single NucleotidePositron-Emission TomographyAmyloid beta-PeptidesBrain-Derived Neurotrophic Factor

Identifiers

PMID30899092
PMCPMC6754794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.