Evidence map›Paper›PMID 30899083›Full record

ArticleLeukemia2019

Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions.

Claus Meyer, Bruno A Lopes, Aurélie Caye-Eude, Hélène Cavé, Chloé Arfeuille, Wendy Cuccuini, Rosemary Sutton, Nicola C Venn, Seung Hwan Oh, Grigory Tsaur and 19 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Review
  3. CrypticGenes · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Targeting the deubiquitinaseOncology reports · 2023
    Review
  8. Haematologica · 2023
    Article
  9. Targeting the undruggable: menin inhibitors ante portas.Journal of cancer research and clinical oncology · 2023
    Review
  10. Article
  11. Preleukemic Fusion Genes Induced via Ionizing Radiation.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Novel Diagnostic and Therapeutic Options forFrontiers in pharmacology · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Claus MeyerDCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Bruno A LopesDCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Aurélie Caye-EudeDepartment of Genetics, AP-HP Robert Debré, Paris Diderot University, Paris, France.
Hélène CavéDepartment of Genetics, AP-HP Robert Debré, Paris Diderot University, Paris, France.
Chloé ArfeuilleDepartment of Genetics, AP-HP Robert Debré, Paris Diderot University, Paris, France.
Wendy CuccuiniDepartment of Cytogenetics, Saint Louis Hospital, Paris, France.
Rosemary SuttonChildren's Cancer Institute Australia, University of NSW Sydney, Sydney, Australia.ORCID http://orcid.org/0000-0002-0188-6005
Nicola C VennChildren's Cancer Institute Australia, University of NSW Sydney, Sydney, Australia.
Seung Hwan OhDCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Grigory TsaurRegional Children Hospital 1, Research Institute of Medical Cell Technologies, Pediatric Oncology and Hematology Center, Ural Federal University named after the first President of Russia BN Yeltsin, Ekaterinburg, Russia.
Gabriele EscherichClinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tobias FeuchtingerDepartment of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Munich, Germany.
Hansen J KosasihMurdoch Children's Research Institute, The Royal Children's Hospital, Flemington Road Parkville, 3052, Victoria, Australia.
Seong L KhawMurdoch Children's Research Institute, The Royal Children's Hospital, Flemington Road Parkville, 3052, Victoria, Australia.
Paul G EkertChildren's Cancer Institute Australia, University of NSW Sydney, Sydney, Australia.ORCID http://orcid.org/0000-0002-2976-8617
Maria S Pombo-de-OliveiraPediatric Hematology-Oncology Program-Research Center, Instituto Nacional de Cancer Rio de Janeiro, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-1507-004X
Audrey BidetLaboratoire d'Hématologie, University Hospital, Brest, CHU de Bordeaux, Bordeaux, France.
Bardya DjahanschiriDepartment of Applied Bioinformatics, Institute of Cell Biology and Neuroscience, Goethe-Universität Frankfurt, Frankfurt am Main, 60438, Germany.
Ingo EbersbergerDepartment of Applied Bioinformatics, Institute of Cell Biology and Neuroscience, Goethe-Universität Frankfurt, Frankfurt am Main, 60438, Germany.
Marketa ZaliovaCLIP, Department of Paediatric Haematology/Oncology, Charles University Prague, 2nd Faculty of Medicine, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-1639-7124
Jan ZunaCLIP, Department of Paediatric Haematology/Oncology, Charles University Prague, 2nd Faculty of Medicine, Prague, Czech Republic.
Zuzana ZermanovaCenter of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Vesa JuvonenDepartment of Clinical Chemistry and Laboratory Division, Turku University Hospital, Turku, Finland.
Renate Panzer GrümayerChildren's Cancer Research Institute, Medical University of Vienna, Vienna, Austria.
Grazia FazioCentro Ricerca Tettamanti, Clinica Pediatrica University of Milano-Bicocca, Monza, Italy.
Gianni CazzanigaCentro Ricerca Tettamanti, Clinica Pediatrica University of Milano-Bicocca, Monza, Italy.ORCID http://orcid.org/0000-0003-2955-4528
Patrizia LargheroDCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Mariana EmerencianoDivision of Clinical Research, Research Center, Instituto Nacional de Cancer, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0003-2337-8420
Rolf MarschalekDCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany. rolf.marschalek@em.uni-frankfurt.de.ORCID http://orcid.org/0000-0003-4870-3445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cohort StudiesHistone-Lysine N-MethyltransferaseHumansLeukemiaMyeloid-Lymphoid Leukemia ProteinRecombinant Fusion ProteinsTranslocation, GeneticUbiquitin ThiolesteraseHistone-Lysine N-MethyltransferaseKMT2A protein, humanMyeloid-Lymphoid Leukemia ProteinRecombinant Fusion ProteinsUbiquitin ThiolesteraseUSP2 protein, human

Identifiers

PMID30899083
PMCPMC6756029

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.