ArticleScientific reports2019
Unveiling the influence of device stiffness in single macromolecule unfolding.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Effects of Temperature and Random Forces in Phase Transformation of Multi-Stable Systems.Entropy (Basel, Switzerland) · 2024Article
- Machine Learning for Shape Memory Graphene Nanoribbons and Applications in Biomedical Engineering.Bioengineering (Basel, Switzerland) · 2022Article
- Capsules Rheology in Carreau-Yasuda Fluids.Nanomaterials (Basel, Switzerland) · 2020Article
- Stick-slip kinetics in a bistable bar immersed in a heat bath.International journal of solids and structures · 2019Article
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Single-molecule stretching experiments on DNA, RNA, and other biological macromolecules opened up the possibility of an impressive progress in many fields of life and medical sciences. The reliability of such experiments may be crucially limited by the possibility of determining the influence of the apparatus on the experimental outputs. Here we deduce a model that let us analytically evaluate such influence, fundamental for the interpretation of Single Molecule Force Spectroscopy experiments and intermolecular interactions phenomena. As we show, our model is coherent with previous numerical results and quantitively reproduce AFM experimental tests on titin macromolecules and P-selectin with variable probe stiffnesses.
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