Evidence map›Paper›PMID 30898977›Full record

ArticleBioscience reports2019

USP39 regulates the cell cycle, survival, and growth of human leukemia cells.

Chunxia Liu, Xiaojian Yao, Ming Li, Yaming Xi, Li Zhao

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. The roles of ubiquitination in AML.Annals of hematology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Whole-Exome Sequencing Implicates theFrontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chunxia LiuDepartment of Hematology, the First Hospital of Lanzhou University, Lanzhou 730000, P.R. China chxliu@lzu.edu.cn zhaoli@lzu.edu.cn.ORCID 0000-0003-4089-788X
Xiaojian YaoDepartment of Hematology, the First Hospital of Lanzhou University, Lanzhou 730000, P.R. China.
Ming LiDepartment of Hematology, the First Hospital of Lanzhou University, Lanzhou 730000, P.R. China.
Yaming XiDepartment of Hematology, the First Hospital of Lanzhou University, Lanzhou 730000, P.R. China.
Li ZhaoDepartment of Hematology, the First Hospital of Lanzhou University, Lanzhou 730000, P.R. China chxliu@lzu.edu.cn zhaoli@lzu.edu.cn.
First Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquitin-specific peptidase 39 (USP39) is one member of the cysteine proteases of the USP family, which represents the largest group of DeUbiquitinases with more than 50 members in humans. The roles of USP39 in human cancer have been widely investigated. However, the roles of USP39 in human leukemia and the underlying mechanism remain unknown. Here we reported the function of USP39 in human leukemia. We observed that the expression of

Indexed as

ApoptosisCaspase 8Cell CycleCell Line, TumorCell ProliferationCell SurvivalGene Expression Regulation, NeoplasticGene Knockdown TechniquesGenetic Predisposition to DiseaseHEK293 CellsHL-60 CellsHumansInterferon Regulatory Factor-1Jurkat CellsLentivirusLeukemiaCaspase 8Interferon Regulatory Factor-1IRF1 protein, humanSP1 protein, humanSp1 Transcription FactorUbiquitin-Specific ProteasesUSP39 protein, humanApoptosisCell cycleCell proliferationIRF1LeukemiaUSP39

Identifiers

PMID30898977
PMCPMC6449567
OpenAlexW2923840250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.