Evidence map›Paper›PMID 30898815›Full record

ArticleBMJ open2019

Cross-sectional study estimating the psychosocial impact of genital warts and other anogenital diseases in South Korea.

Taek Sang Lee, Smita Kothari-Talwar, Puneet K Singhal, Karen Yee, Amit Kulkarni, Nuria Lara, Montserrat Roset, Anna R Giuliano, Suzanne M Garland, Woong Ju

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Taek Sang LeeDepartment of Obstetrics and Gynecology, SMG-SNU Boramae Medical Center, Seoul, South Korea.
Smita Kothari-TalwarMerck and Co Inc, Kenilworth, New Jersey, USA.
Puneet K SinghalMerck and Co Inc, Kenilworth, New Jersey, USA.
Karen YeeCubist Pharmaceuticals Inc, Lexington, Massachusetts, USA.
Amit KulkarniMerck and Co Inc, Kenilworth, New Jersey, USA.
Nuria LaraReal World Evidence Solutions, IQVIA, Barcelona, Spain.
Montserrat RosetReal World Evidence Solutions, IQVIA, Barcelona, Spain.
Anna R GiulianoLee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Suzanne M GarlandMicrobiology and Infectious Diseases Department, The Royal Women's Hospital, Parkville, Victoria, Australia.
Woong JuSchool of Medicine, Ewha Womans University, Seoul, South Korea.
Merck & Co., Inc., Rahway, NJ, USA (United States) · USCubist Pharmaceuticals (United States) · USEwha Womans University · KRMoffitt Cancer Center · USRoyal Women's Hospital · AUSNUH SMG-SNU Boramae Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate self-reported human papillomavirus (HPV) disease-related psychosocial impact among male and female patients in South Korea.

designIn this multicentre cross-sectional study, psychosocial impacts were estimated using a one-time survey capturing HPV Impact Profile (HIP) results, CuestionarioEspecifico en Condilomas Acuminados (CECA; in Spanish)-'Specific questionnaire for Condylomata Acuminata' and the EuroQol-5 Dimension (EQ-5D) surveys. Student's t-tests or Mann-Whitney U tests were used for continuous comparisons; χ

setting5098 clinics throughout Seoul, Busan, Daegu, Kwangju and Daejeon (South Korea).

participantsPatients with and without genital warts (GW) (males) and selected HPV diseases (females) visiting primary care physicians, obstetricians/gynaecologists, urologists and dermatologists with 2-30 years experience.

resultsOf 150 male and 250 female patients, HIP scores showed 85.3% of male patients with GW and 32.0% without reported moderate psychological impact (p<0.0001). In categorised total scores, 88.5% of female patients with and 66.0% without selected HPV-related diseases reported moderate or high psychological impacts (p=0.0004). In the CECA questionnaire, male patients had mean (SD) scores of 10.51 (3.79) in 'emotional health' and 15.90 (6.13) in 'sexual activity'. Female patients with GW reported lower scores in both dimensions with mean scores of 7.18 (4.17) in 'emotional health' and 10.97 (5.80) in 'sexual activity' (p<0.0001), indicating worse health-related quality of life (HRQoL). For the EQ-5D, male patients with GW reported lower mean Visual Analogue Scale (VAS) scores than those without (75.1 vs 81.13, p<0.0135). Mean VAS score and utility values were lower for females with HPV-related diseases than those without (72.18 vs 76.86 and 0.90 vs 0.94, respectively).

conclusionIn South Korea, GW in men and HPV-related diseases in women negatively impact patient well-being and HRQoL scores. Among women, those with GW suffered a greater psychosocial impact than those with other selected HPV-related diseases.

Indexed as

Cost of IllnessAdultAnxietyCross-Sectional StudiesFemaleHealth StatusHumansMaleMiddle AgedPapillomavirus InfectionsPatient SatisfactionQuality of LifeRepublic of KoreaStress, PsychologicalSurveys and Questionnairesgenital wartspsychosocial impactSouth Korea

Identifiers

PMID30898815
PMCPMC6475443
OpenAlexW2924479138

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.