Evidence map›Paper›PMID 30898331›Full record

Trial reportJournal of substance abuse treatment2019

Mindfulness-based relapse prevention for alcohol dependence: Findings from a randomized controlled trial.

Aleksandra E Zgierska, Cindy A Burzinski, Marlon P Mundt, Andrew S McClintock, Jennifer Cox, Christopher L Coe, Michael M Miller, Michael F Fleming

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022
    Pooled it
  2. Mindfulness-based interventions for substance use disorders.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Pooled it
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  14. The (In)flexible self: Psychopathology, mindfulness, and neuroscience.International journal of clinical and health psychology : IJCHP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksandra E ZgierskaUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America. Electronic address: Aleksandra.Zgierska@fammed.wisc.edu.
Cindy A BurzinskiUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America. Electronic address: Cindy.Burzinski@fammed.wisc.edu.
Marlon P MundtUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America. Electronic address: Marlon.Mundt@fammed.wisc.edu.
Andrew S McClintockUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America. Electronic address: asmcclintock@wisc.edu.
Jennifer CoxUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America. Electronic address: jcox@uwhealth.org.
Christopher L CoeUniversity of Wisconsin-Madison, Harlow Center for Biological Psychology, 22 N Charter St, Madison, WI 53715, United States of America. Electronic address: ccoe@wisc.edu.
Michael M MillerUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Psychiatry, 6001 Research Park Boulevard, Madison, WI 53719, United States of America. Electronic address: michael.miller@uwmf.wisc.edu.
Michael F FlemingUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI 53715, United States of America; Northwestern University, Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences, Abbott Hall Suite 1320, 710 N Lake Shore Drive, Chicago, IL 60611, United States of America. Electronic address: m-fleming@northwestern.edu.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Mindfulness Meditation for Alcohol Relapse PreventionK23AA017508 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI ZGIERSKA, ALEKSANDRA EWA · 2009 to 2013
$918k
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NIAAA NIH HHS K23 AA017508
6 · The paper itself

Abstract

objectivesTo assess the effects of mindfulness-based relapse prevention for alcohol dependence (MBRP-A) intervention on drinking and related consequences.

methods123 alcohol-dependent adults in early recovery, recruited from outpatient treatment programs, were randomly assigned to MBRP-A (intervention plus usual-care; N = 64) or Control (usual-care-alone; N = 59) group. MBRP-A consisted of eight-weekly sessions and home practice. Outcomes were assessed at baseline, 8 weeks and 26 weeks (18 weeks post-intervention), and compared between groups using repeated measures analysis.

resultsOutcome analysis included 112 participants (57 MBRP-A; 55 Control) who provided follow-up data. Participants were 41.0 ± 12.2 years old, 56.2% male, and 91% white. Prior to "quit date," they reported drinking on 59.4 ± 34.8% (averaging 6.1 ± 5.0 drinks/day) and heavy drinking (HD) on 50.4 ± 35.5% of days. Their drinking reduced after the "quit date" (before enrollment) to 0.4 ± 1.7% (HD: 0.1 ± 0.7%) of days. At 26 weeks, the MBRP-A and control groups reported any drinking on 11.5 ± 22.5% and 5.9 ± 11.6% of days and HD on 4.5 ± 9.3% and 3.2 ± 8.7% of days, respectively, without between-group differences (ps ≥ 0.05) in drinking or related consequences during the follow-up period. Three MBRP-A participants reported "relapse," defined as three-consecutive HD days, during the study. Subgroup analysis indicated that greater adherence to session attendance and weekly home practice minutes were associated with improved outcomes.

conclusionsMBRP-A as an adjunct to usual-care did not show to improve outcomes in alcohol-dependent adults in early recovery compared to usual-care-alone; a return to drinking and relapse to HD were rare in both groups. However, greater adherence to MBRP-A intervention may improve long-term drinking-related outcomes.

Indexed as

MindfulnessNegotiatingAdultAlcoholismFemaleHumansMaleMiddle AgedSecondary PreventionTreatment OutcomeAlcohol dependenceAlcoholismMeditationMindfulnessRelapse prevention

Identifiers

PMID30898331
PMCPMC6508889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.