Evidence map›Paper›PMID 30898209›Full record

ReviewJournal of the American College of Cardiology2019

Anticoagulation Strategies in Patients With Cancer: JACC Review Topic of the Week.

Ramya C Mosarla, Muthiah Vaduganathan, Arman Qamar, Javid Moslehi, Gregory Piazza, Robert P Giugliano

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 7 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 7 syntheses or guidelines pooled it, 175 citations in OpenAlex.

  1. Catheter ablation in patients with atrial fibrillation and cancer: a systematic review and updated meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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  8. Review
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  13. Hemostasis at the edge between physiology and cancer.Internal and emergency medicine · 2026
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  16. Observational
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ramya C MosarlaDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Muthiah VaduganathanBrigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/mvaduganathan.
Arman QamarTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/AqamarMD.
Javid MoslehiCardio-Oncology Program, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Gregory PiazzaBrigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, Massachusetts.
Robert P GiuglianoTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: rgiugliano@partners.org.
Brigham and Women's Hospital · USTwitter (United States) · USMassachusetts General Hospital · USVanderbilt University Medical Center · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
TRAINING PROGRAM IN CARDIOVASCULAR RESEARCHT32HL007604 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MARK W FEINBERG · 1985 to 2026
$19.0M
Novel mechanisms and predictors of VEGF receptor inhibitor-associated hypertensionR56HL141466 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MOSLEHI, JAVID J · 2018 to 2018
$613k
NCATS NIH HHS UL1 TR002541NHLBI NIH HHS R56 HL141466NHLBI NIH HHS T32 HL007604
6 · The paper itself

Abstract

Patients with active cancer are at an increased risk of arterial and venous thromboembolism (VTE) and bleeding events. Historically, in patients with cancer, low molecular weight heparins have been preferred for treatment of VTE, whereas warfarin has been the standard anticoagulant for stroke prevention in patients with atrial fibrillation (AF). More recently, direct oral anticoagulants (DOACs) have been demonstrated to reduce the risk of venous and arterial thromboembolism in large randomized clinical trials of patients with VTE and AF, respectively, thus providing an attractive oral dosing option that does not require routine laboratory monitoring. In this review, we summarize available clinical trial data and guideline recommendations, and outline a practical approach to anticoagulation management of VTE and AF in cancer.

Indexed as

AnticoagulantsAtrial FibrillationNeoplasmsThromboembolismBlood CoagulationClinical Trials as TopicHumansPractice Guidelines as TopicAnticoagulantsanticoagulationatrial fibrillationbleedingcancercardio-oncologyvenous thromboembolism

Identifiers

PMID30898209
PMCPMC7957366
OpenAlexW2923737794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.