ArticleBMC genomics2019
Genome-wide analysis of three histone marks and gene expression in Paulownia fortunei with phytoplasma infection.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Forest tree-pathogen interactions under climate change.Essays in biochemistry · 2026Review
- Integrated analysis of ATAC-seq and RNA-seq reveals the TCP-ARF molecular module related to pathogenic process of phytoplasma infection in Paulownia fortunei.BMC genomics · 2026Article
- Integrating Single-Cell and Spatial Multi-Omics to Decode Plant-Microbe Interactions at Cellular Resolution.Microorganisms · 2026Review
- Epigenetic responses of trees to environmental stress in the context of climate change.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Biochemical Defence of Plants against Parasitic Nematodes.Plants (Basel, Switzerland) · 2024Review
- Transcriptomic Profiling of Sugarcane White Leaf (SCWL) Canes during Maturation Phase.Plants (Basel, Switzerland) · 2024Article
- Paulownia Witches' Broom Disease: A Comprehensive Review.Microorganisms · 2024Review
- Rice responds to Spodoptera frugiperda infestation via epigenetic regulation of H3K9ac in the jasmonic acid signaling and phenylpropanoid biosynthesis pathways.Plant cell reports · 2024Article
- Transcriptomic and methylation analysis of susceptible and tolerant grapevine genotypes following Plasmopara viticola infection.Physiologia plantarum · 2022Article
- Integrative Investigation of Root-Related mRNAs, lncRNAs and circRNAs of "Muscat Hamburg" (Genes · 2022Article
- OMICs, Epigenetics, and Genome Editing Techniques for Food and Nutritional Security.Plants (Basel, Switzerland) · 2021Review
- Genome-wide shifts in histone modifications at early stage of rice infection with Meloidogyne graminicola.Molecular plant pathology · 2021Article
- Molecular memory ofHorticulture research · 2020Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPaulownia withes'-broom (PaWB) disease caused by phytoplasma is a serious infectious disease for Paulownia. However, the underlying molecular pathogenesis is not fully understood. Recent studies have demonstrated that histone modifications could play a role in plant defense responses to pathogens. But there is still no available genome-wide histone modification data in non-model ligneous species infected with phytoplasma.
resultsHere, we provided the first genome-wide profiles of three histone marks (H3K4me3, H3K36me3 and H3K9ac) in Paulownia fortunei under phytoplasma stress by using chromatin immunoprecipitation sequencing (ChIP-Seq). We found that H3K4me3, H3K36me3 and H3K9ac were mainly enriched in the genic regions in P. fortunei with (PFI) and without (PF) phytoplasma infection. ChIP-Seq analysis revealed 1738, 986, and 2577 genes were differentially modified by H3K4me3, H3K36me3 and H3K9ac marks in PFI under phytoplasma infection, respectively. The functional analysis of these genes suggested that most of them were mainly involved in metabolic pathways, biosynthesis of secondary metabolites, phenylpropanoid biosynthesis, plant-pathogen interaction and plant hormone signal transduction. In addition, the combinational analysis of ChIP-Seq and RNA-Seq showed that differential histone methylation and acetylation only affected a small subset of phytoplasma-responsive genes.
conclusionsTaken together, this is the first report of integrated analysis of histone modifications and gene expression involved in Paulownia-phytoplasma interaction. Our results will provide the valuable resources for the mechanism studies of gene regulation in non-model plants upon pathogens attack.
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