Evidence map›Paper›PMID 30898095›Full record

ArticleBMC public health2019

Correlates of nonadherence to key population-led HIV pre-exposure prophylaxis services among Thai men who have sex with men and transgender women.

Pich Seekaew, Ezie Nguyen, Thanthip Sungsing, Jureeporn Jantarapakde, Supabhorn Pengnonyang, Deondara Trachunthong, Pravit Mingkwanrungruang, Waraporn Sirisakyot, Pattareeya Phiayura, Phubet Panpet and 12 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05243030 (Adapting Effective mHealth Interventions to Improve Uptake and Adherence of the HIV Pre-exposure Prophylaxis), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05243030 nacompletednot on this mapstarted 2022, after this paper: background citation

Adapting Effective mHealth Interventions to Improve Uptake and Adherence of the HIV Pre-exposure Prophylaxis (PrEP) in Thai Young Men Who Have Sex With Men (MSM).

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2022 to 2025Enrolled119ConditionsPre-Exposure ProphylaxisArmsMotivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP), Motivational Interactive Text Messaging (MTM), Standard PrEP Counseling
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pre-exposure Prophylaxis Adherence Among Men Who Have Sex With Men: A Systematic Review and Meta-analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 2 countries.

Pich SeekaewPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand. pich@trcarc.org.ORCID http://orcid.org/0000-0002-3941-3457
Ezie NguyenPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Thanthip SungsingPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Jureeporn JantarapakdePREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Supabhorn PengnonyangPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Deondara TrachunthongPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Pravit MingkwanrungruangPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Waraporn SirisakyotPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Pattareeya PhiayuraPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Phubet PanpetRainbow Sky Association of Thailand, Bangkok, Thailand.
Phathranis MeekruaService Workers IN Group (SWING) Foundation, Bangkok, Thailand.
Nanthika PrawepraiSisters Foundation, Pattaya, Chonburi, Thailand.
Fonthip SuwanRainbow Sky Association of Thailand, Songkhla, Thailand.
Supakarn SangtongMPlus Foundation, Chiang Mai, Thailand.
Pornpichit BrutratSWING Foundation, Pattaya, Chonburi, Thailand.
Tashada WongsriCaremat Foundation, Chiang Mai, Thailand.
Panus Rattakittvijun Na NakornPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Stephen MillsFHI 360 and LINKAGES Project, Bangkok, Thailand.
Matthew AveryFHI 360 and LINKAGES Project, Bangkok, Thailand.
Ravipa VannakitOffice of Public Health, U.S. Agency for International Development Regional Development Mission for Asia, Bangkok, Thailand.
Praphan PhanuphakPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Nittaya PhanuphakPREVENTION, the Thai Red Cross AIDS Research Centre, 104 Rajdamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Thai Red Cross Society · THThai Health Promotion Foundation · THUniversity of Southern California · US

Funding

United States Agency for International Development AID-OAA-A-14-00045
6 · The paper itself

Abstract

backgroundBased on government estimates from the Asian Epidemic Model, new infections among men who have sex with men (MSM) and transgender women (TGW) in Thailand are forecast to proportionally increase over time. Daily oral Pre-exposure prophylaxis (PrEP) protects against HIV acquisition when used as prescribed. The "Princess PrEP" program is the first key population-led (PrEP) initiative under Thai royal patronage with an aim to scale up countrywide implementation of PrEP.

methodsRetention in and adherence to key population-led HIV PrEP services among HIV-uninfected Thai MSM and TGW was examined in four provinces: Bangkok, Chonburi, Chiang Mai, and Songkhla. HIV, HBsAg, creatinine tests, and self-administered questionnaires were performed during baseline measures. Participants were followed up after month 1, at month 3, then every 3 months. Correlates of nonadherence and loss to follow up at 1 month were assessed using linear regression models.

results37.4% of the participants reported low adherence to services (≤ 3 pills/week or missed clinic schedule at month 1). Factors associated with low adherence included younger age (25 years and under) (adjusted odds ratio (aOR): 1.49, 95% confidence interval (95% CI: 1.01-2.21, p = 0.044), being a TGW (aOR: 2.2, 95% CI: 1.27-3.83, p = 0.005), and whether the participant had not previously accessed services at the clinic (aOR = 1.68, 95% CI: 1.03-2.76, p = 0.04). Additionally, participants in Chonburi (the only TGW site) showed significantly lower adherence than those in the other three provinces (aOR: 2.91, 95% CI: 1.55-5.45, p = 0.001).

conclusionUrgent, innovative interventions for early PrEP adherence support among vulnerable sub-populations such as younger users, TGW, and new clients are needed to maximize prevention strategy in Thailand.

Indexed as

Drug MonitoringAdultFemaleHIV InfectionsHomosexuality, MaleHumansMalePre-Exposure ProphylaxisRisk FactorsThailandTransgender PersonsYoung AdultHIV preventionKey population-ledMSMPre-exposure prophylaxisPrEP adherenceTransgender women

Identifiers

PMID30898095
PMCPMC6429797
OpenAlexW2944093378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.