Evidence map›Paper›PMID 30897938›Full record

ArticleAIDS care2018

Factors associated with viral suppression among HIV-positive Kenyan gay and bisexual men who have sex with men.

Colin P Kunzweiler, Robert C Bailey, Supriya D Mehta, Duncan O Okall, Eve Obondi, Gaston Djomand, Boaz Otieno Nyunya, Fredrick O Otieno, Susan M Graham

Abstract read
In one paragraph

Article in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
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  9. Review
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  15. Narratives of Change From Gay and Bisexual Men Living With HIV in an Emotional Well-Being Intervention.AIDS education and prevention : official publication of the International Society for AIDS Education · 2022
    Article
  16. Review
  17. Mental Health Challenges and Needs among Sexual and Gender Minority People in Western Kenya.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Colin P Kunzweilera Division of Epidemiology and Biostatistics, School of Public Health , University of Illinois at Chicago , Chicago , IL , USA.
Robert C Baileya Division of Epidemiology and Biostatistics, School of Public Health , University of Illinois at Chicago , Chicago , IL , USA.
Supriya D Mehtaa Division of Epidemiology and Biostatistics, School of Public Health , University of Illinois at Chicago , Chicago , IL , USA.
Duncan O Okallb Nyanza Reproductive Health Society , Kisumu , Kenya.
Eve Obondib Nyanza Reproductive Health Society , Kisumu , Kenya.
Gaston Djomandc Division of Global HIV/AIDS and Tuberculosis , Centers for Disease Control and Prevention , Atlanta , GA , USA.
Boaz Otieno Nyunyad Division of Global HIV/AIDS , Centers for Disease Control and Prevention , Kisumu , Kenya.
Fredrick O Otienob Nyanza Reproductive Health Society , Kisumu , Kenya.
Susan M Grahame Departments of Medicine, Global Health, and Epidemiology , University of Washington , Seattle , WA , USA.ORCID 0000-0001-7847-8686

Funding

CGH CDC HHS U01 GH000762Intramural CDC HHS CC999999PEPFAR
6 · The paper itself

Abstract

The UNAIDS 90-90-90 target has prioritized achieving high rates of viral suppression. We identified factors associated with viral suppression among HIV-positive gay, bisexual, and other men who have sex with men (GBMSM) in Kisumu, Kenya. HIV-positive participants in the Anza Mapema study were offered antiretroviral therapy (ART) regardless of CD4 count. HIV viral load was assessed at baseline and after 6 and 12 months of follow-up. Viral suppression was defined as <1,000 copies/mL. Sociodemographic, sexual behaviors, and psychosocial characteristics were assessed via audio computer-assisted self interview. We used generalized estimating equations to estimate the associations between baseline and time-dependent predictors and viral suppression at 6 and 12 months. Seventy-five HIV-positive men were enrolled in the Anza Mapema study, of which 63 had at least one viral load measured during follow-up. Among 52 men with a viral load measure at month 6, 37 (71%) were on ART and virally suppressed. Among 59 men with a viral load measure at month 12, 37 (63%) were on ART and virally suppressed. In the final multivariable model, men who reported receptive or versatile sexual position during anal intercourse with a male partner had reduced odds of viral suppression (aOR = 0.20; 95% CI: 0.08-0.50). Greater levels of coping self-efficacy were associated with increased odds of viral suppression (aOR = 1.10; 95% CI: 1.03-1.16). Despite extensive initiation, retention, and adherence support, the rate of viral suppression in this population did not meet the UNAIDS 90-90-90 target (81% for individuals aware of their HIV status). Pervasive stigma against male-male sex, especially men who practice receptive anal sex, may underlie our findings, which highlight the need for advocacy and stigma reduction efforts. Because coping self-efficacy was a protective factor, efforts to promote resilience in addition to healthy sexual identity development may lead to improved care outcomes among GBMSM in this area.

Indexed as

Homosexuality, MaleSexual and Gender MinoritiesViral LoadAdultAnti-HIV AgentsAwarenessCD4 Lymphocyte CountHIVHIV InfectionsHumansKenyaMaleMiddle AgedSexual PartnersSocial StigmaYoung AdultAnti-HIV AgentsGay and bisexual men who have sex with menGBMSMHIVKenyaMSMviral suppression

Identifiers

PMID30897938
PMCPMC10669762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.