Evidence map›Paper›PMID 30897843›Full record

ArticleInternational journal of molecular sciences2019

Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads.

Caroline Mangare, Sabine Tischer-Zimmermann, Sebastian B Riese, Anna C Dragon, Immo Prinz, Rainer Blasczyk, Britta Maecker-Kolhoff, Britta Eiz-Vesper

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caroline MangareInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. mangare.caroline@mh-hannover.de.
Sabine Tischer-ZimmermannInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. tischer-zimmermann.sabine@mh-hannover.de.
Sebastian B RieseInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. riese.sebastian@mh-hannover.de.
Anna C DragonInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. dragon.anna@mh-hannover.de.
Immo PrinzInstitute of Immunology, Hannover Medical School, 30625 Hannover, Germany. prinz.immo@mh-hannover.de.
Rainer BlasczykInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. blasczyk.rainer@mh-hannover.de.
Britta Maecker-KolhoffIntegrated Research and Treatment Center (IFB-Tx), Hannover Medical School, 30625 Hannover, Germany. maecker-kolhoff.britta@mh-hannover.de.
Britta Eiz-VesperInstitute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany. eiz-vesper.britta@mh-hannover.de.

Funding

Deutsche Forschungsgemeinschaft SFB900
6 · The paper itself

Abstract

Viral infections and reactivations remain a serious obstacle to successful hematopoietic stem cell transplantation (HSCT). When antiviral drug treatment fails, adoptive virus-specific T-cell transfer provides an effective alternative. Assuming that naive T cells (T

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytomegalovirusGraft vs Host DiseaseHumansImmunophenotypingImmunotherapyLeukocyte Common AntigensL-SelectinMicrospheresT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsLeukocyte Common AntigensL-Selectincytomegalovirus (CMV)donor lymphocyte infusions (DLIs)graft versus host disease (GvHD)naive T-cell depletion

Identifiers

PMID30897843
PMCPMC6471767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.