Evidence map›Paper›PMID 30897831›Full record

ArticleMolecules (Basel, Switzerland)2019

Extracts from Fermented Black Garlic Exhibit a Hepatoprotective Effect on Acute Hepatic Injury.

Jen-Chieh Tsai, Yi-An Chen, Jung-Tsung Wu, Kuan-Chen Cheng, Ping-Shan Lai, Keng-Fan Liu, Yung-Kai Lin, Yu-Tsang Huang, Chang-Wei Hsieh

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Anti-Cancer and Anti-Inflammatory Properties of Black Garlic.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jen-Chieh TsaiDepartment of Medicinal Botanicals and Health Applications, Da-Yeh University, Chang-Hua 51591, Taiwan. jenchieh@mail.dyu.edu.tw.
Yi-An ChenCollege of Biotechnology and Bioresources, Da-Yeh University, Changhua County 51591, Taiwan. anncerita@gmail.com.
Jung-Tsung WuCollege of Biotechnology and Bioresources, Da-Yeh University, Changhua County 51591, Taiwan. chen.ben495@gmail.com.
Kuan-Chen ChengInstitute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan. kccheng@ntu.edu.tw.
Ping-Shan LaiDepartment of Chemistry, National Chung Hsing University, Taichung 402, Taiwan. pslai@email.nchu.edu.tw.
Keng-Fan LiuSchool of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, Taichung 40402, Taiwan. stella89132@yahoo.com.tw.
Yung-Kai LinGlobal Research and Industry Alliance Center, National Chung Hsing University, Taichung 402, Taiwan. nitrite.tw@gmail.com.
Yu-Tsang HuangMenglinbeier Clinic, Taichung 407, Taiwan. yuhchanghuang@gmail.com.
Chang-Wei HsiehDepartment of Food science and biotechnology, National Chung Hsing University, Taichung 402, Taiwan. welson@nchu.edu.tw.
Dayeh University · TWNational Chung Hsing University · TWChina Medical University · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanism of hepatoprotective compounds is usually related to its antioxidant or anti-inflammatory effects. Black garlic is produced from garlic by heat treatment and its anti-inflammatory activity has been previously reported. Therefore, the aim of this study was to investigate the hepatoprotective effect of five different extracts of black garlic against carbon tetrachloride (CCl₄)-induced acute hepatic injury (AHI). In this study, mice in the control, CCl₄, silymarin, and black garlic groups were orally administered distilled water, silymarin, and different fraction extracts of black garlic, respectively, after CCl₄ was injected intraperitoneally to induce AHI. The results revealed that the

Indexed as

Acute Lung InjuryAlanine TransaminaseAlkaline PhosphataseAnimalsAntioxidantsCarbon TetrachlorideFermentationGarlicGlutathione PeroxidaseGlutathione ReductaseLiverMaleMalondialdehydePlant ExtractsRatsSilymarinAlanine TransaminaseAlkaline PhosphataseAntioxidantsCarbon TetrachlorideGlutathione PeroxidaseGlutathione ReductaseMalondialdehydePlant ExtractsSilymarinSuperoxide DismutaseTumor Necrosis Factor-alphaacute hepatic injuryanti-inflammatoryantioxidantblack garliccarbon tetrachloride

Identifiers

PMID30897831
PMCPMC6471182
OpenAlexW2925040540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.