Evidence map›Paper›PMID 30897362›Full record

ArticleNeuron2019

Dissecting the Toxic Effects of Zika Virus Proteins on Neural Progenitor Cells.

Raiane O Ferreira, Patricia P Garcez

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects ofFrontiers in molecular neuroscience · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Raiane O FerreiraInstitute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Patricia P GarcezInstitute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: ppgarcez@icb.ufrj.br.
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms by which Zika virus (ZIKV) disrupts neurogenesis and causes microcephaly are poorly understood. In this issue of Neuron, Li et al. (2019) demonstrate that ZIKV protease NS2B-NS3 heterodimers cleave Septin-2 and lead to cytokinesis defects.

Indexed as

MicrocephalyNeural Stem CellsZika VirusZika Virus InfectionHumansSeptinsSeptinsbrain malformationcongenital Zika syndromecytokinesismicrocephalyneural stem cellspathogenesisseptinZika virus

Identifiers

PMID30897362
OpenAlexW2924894218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.