Evidence map›Paper›PMID 30897272›Full record

Trial reportJournal of diabetes investigation2019

Difference in the prevalence of gestational diabetes mellitus according to gestational age at 75-g oral glucose tolerance test in Japan: The Japan Assessment of Gestational Diabetes Mellitus Screening trial.

Noriyuki Iwama, Takashi Sugiyama, Hirohito Metoki, Hideto Kusaka, Nobuo Yaegashi, Norimasa Sagawa, Yuji Hiramatsu, Nagayasu Toyoda, JAGS Group

Abstract readClinical Trial
In one paragraph

Trial report in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noriyuki IwamaCenter for Perinatal Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan.
Takashi SugiyamaDepartment of Obstetrics and Gynecology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.ORCID https://orcid.org/0000-0002-3715-0075
Hirohito MetokiDivision of Public Health, Hygiene and Epidemiology, Tohoku Medical Pharmaceutical University, Sendai, Miyagi, Japan.
Hideto KusakaDepartment of Obstetrics and Gynecology, National Hospital Organization Mie Chuo Medical Center, Tsu, Mie, Japan.
Nobuo YaegashiDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Norimasa SagawaDepartment of Obstetrics and Gynecology, Rakuwakai Otowa Hospital, Kyoto, Japan.
Yuji HiramatsuDepartment of Obstetrics and Gynecology, Okayama City General Medical Center, Okayama, Japan.
Nagayasu ToyodaSuzuka University of Medical Science, Suzuka, Mie, Japan.
JAGS Group

Funding

Ministry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan 200100372AMinistry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan 200200370AMinistry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan 200300296A
6 · The paper itself

Abstract

AIMS/

introductionTo evaluate the differences in the results of 75-g oral glucose tolerance tests (OGTTs) according to gestational age in Japan. MATERIALS AND

methodsIn this prospective cohort study, 2,578 pregnant women were divided into three categories based on their gestational age during the 75-g OGTT: <14 weeks' gestation, 14-23 weeks' gestation and 24-32 weeks' gestation. The association between gestational age and the results of the 75-g OGTT were evaluated using multivariable analysis.

resultsEarly gestational age was associated with high fasting plasma glucose levels at the time of the 75-g OGTT, and low corresponding 1-h and 2-h plasma glucose levels. Compared with women with a gestational age of 24-32 weeks, women who had undergone the 75-g OGTT at <14 weeks' gestation had significantly higher odds of gestational diabetes mellitus diagnosis based on the currently used criteria in Japan (adjusted odds ratio 1.42, 95% confidence interval 1.07-1.90).

conclusionsThe results of the 75-g OGTT varied by gestational age. The use of the same 75-g OGTT cut-off values for the diagnosis of gestational diabetes mellitus, regardless of gestational age, might lead to increases in the prevalence of gestational diabetes mellitus diagnosis in Japan.

Indexed as

Gestational AgeAdultBiomarkersBlood GlucoseDiabetes, GestationalFemaleFollow-Up StudiesGlucose Tolerance TestHumansJapanPregnancyPrevalencePrognosisProspective StudiesRisk AssessmentBiomarkersBlood Glucose75-g Oral glucose tolerance testGestational ageGestational diabetes mellitus

Identifiers

PMID30897272
PMCPMC6825953

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.