Evidence map›Paper›PMID 30897205›Full record

ReviewImmunology2019

Origins of CD4

Quynh P Nguyen, Tianda Z Deng, Deborah A Witherden, Ananda W Goldrath

Abstract readReview
In one paragraph

Review in Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed.

  1. Article
  2. PD-1 Inhibits CD4+ TRM-Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Tumor-embedded Immunity and TRM Cell Functions in Cancer.Mini reviews in medicinal chemistry · 2026
    Review
  8. Review
  9. Article
  10. CD4Immunology and cell biology · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quynh P NguyenDivision of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
Tianda Z DengDivision of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
Deborah A WitherdenDivision of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
Ananda W GoldrathDivision of Biological Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-5900-508X

Funding

TF regulation of CD8 and CD4 T cell memory in both systemic and dermal infectionU19AI109976 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN · 2014 to 2018
$10.5M
Regulation of T cell immunity to viral infectionR01AI072117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2008 to 2022
$5.4M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
NIAID NIH HHS R01 AI072117NIAID NIH HHS U19 AI109976NIAMS NIH HHS T32 AR064194
6 · The paper itself

Abstract

In response to infection, naive CD4

Indexed as

AnimalsBlood CirculationCD4-Positive T-LymphocytesCell DifferentiationHomeostasisHumansImmunity, InnateImmunologic MemoryIntestinal MucosaLungLymphocyte ActivationSkinprotective immunityT helper

Identifiers

PMID30897205
PMCPMC6459775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.