ArticleEuropean journal of public health2019
Adverse childhood experiences, childhood relationships and associated substance use and mental health in young Europeans.
Article in European journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Resilience after adversity: an umbrella review of adversity protective factors and resilience-promoting interventions.Frontiers in psychiatry · 2024Pooled it
- Health and financial costs of adverse childhood experiences in 28 European countries: a systematic review and meta-analysis.The Lancet. Public health · 2021Pooled it
- Targets for intervention to prevent substance use in young people exposed to childhood adversity: A systematic review.PloS one · 2021Pooled it
- From Home to Hallways: How Adverse Childhood Experiences and School Context Shape Student Relationship Development.The Journal of school health · 2026Article
- Predicting Substance Use in Young Adults: The Role of Childhood Adversity.Medicina (Kaunas, Lithuania) · 2026Article
- Tipping the scales: the predictive utility of the PCE-ACE ratio for criminogenic and wellbeing outcomes in a general adult population.Health & justice · 2026Article
- Adverse childhood experiences, and violence and criminal justice outcomes in adulthood-the moderating role of protective and compensatory childhood experiences.BMC medicine · 2025Article
- Adverse childhood experiences as predictors of alcohol and tobacco addiction risk among college students in Delhi-NCR, India.Scientific reports · 2025Article
- The Role of Childhood Adversity and Social Drivers of Health in Subjective Cognitive Decline.Preventing chronic disease · 2025Article
- Pathways of Intergenerational Risk: Examining the Association Between Maternal Adverse Childhood Experiences and Child Socio-Emotional and Behavioral Concerns at 8 Years of Age.Child maltreatment · 2025Article
- Adverse childhood experiences, resilience, and syringe services program attendance among persons who inject drugs in Northeast Georgia, USA: A mediation analysis.Drug and alcohol dependence reports · 2025Article
- Adolescents' Adverse Childhood Experiences, Poor Mental Health, and Substance Use During the COVID-19 Pandemic.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Impact pathways of adverse childhood experiences on infectious diseases among substance abusers in border regions: structural equation modeling.Frontiers in public health · 2025Article
- Prevalence and impact of adverse childhood experiences and extrafamilial violence: a representative survey of adults in Northern Ireland.BMJ public health · 2025Article
- Stress and substance use disorders: risk, relapse, and treatment outcomes.The Journal of clinical investigation · 2024Review
- Co-occurring trauma- and stressor-related and substance-related disorders in youth: A narrative review.Medical research archives · 2024Article
- Patterns of Trauma Among Youth Seeking Mental Health Services at a Community-Based Clinic: A Latent Class Analysis Approach.Research on child and adolescent psychopathology · 2023Article
- Problematic parental substance use, childhood family structures and adverse outcomes in young adulthood.Nordisk alkohol- & narkotikatidskrift : NAT · 2023Article
- Adverse childhood experiences and their association with substance use disorders in adulthood: A general population study (Young-HUNT).Addictive behaviors reports · 2023Article
- Youth Suicide and Self-Harm: Latent Class Profiles of Adversity and the Moderating Roles of Perceived Support and Sense of Safety.Journal of youth and adolescence · 2023Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdverse childhood experiences (ACEs) can increase risks of health-harming behaviours and poor health throughout life. While increases in risk may be affected by resilience resources such as supportive childhood relationships, to date few studies have explored these effects.
methodsWe combined data from cross-sectional ACE studies among young adults (n = 14 661) in educational institutions in 10 European countries. Nine ACE types, childhood relationships and six health outcomes (early alcohol initiation, problem alcohol use, smoking, drug use, therapy, suicide attempt) were explored. Multivariate modelling estimated relationships between ACE counts, supportive childhood relationships and health outcomes.
resultsAlmost half (46.2%) of participants reported ≥1 ACE and 5.6% reported ≥4 ACEs. Risks of all outcomes increased with ACE count. In individuals with ≥4 ACEs (vs. 0 ACEs), adjusted odds ratios ranged from 2.01 (95% CIs: 1.70-2.38) for smoking to 17.68 (95% CIs: 12.93-24.17) for suicide attempt. Supportive childhood relationships were independently associated with moderating risks of smoking, problem alcohol use, therapy and suicide attempt. In those with ≥4 ACEs, adjusted proportions reporting suicide attempt reduced from 23% with low supportive childhood relationships to 13% with higher support. Equivalent reductions were 25% to 20% for therapy, 23% to 17% for problem drinking and 34% to 32% for smoking.
conclusionsACEs are strongly associated with substance use and mental illness. Harmful relationships are moderated by resilience factors such as supportive childhood relationships. Whilst ACEs continue to affect many children, better prevention measures and interventions that enhance resilience to the life-long impacts of toxic childhood stress are required.
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