ArticlePloS one2019
Analgesic use among the Brazilian population: Results from the National Survey on Access, Use and Promotion of Rational Use of Medicines (PNAUM).
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Use of dipyrone during pregnancy and risk of congenital anomalies: a systematic review.European journal of clinical pharmacology · 2025Pooled it
- Dipyrone use in Brazil: clinical conditions, sociodemographic characteristics, population attitudes and perceptions.Cadernos de saude publica · 2026Article
- Anvisa authorization for electronic prescriptions of controlled substances: implications for equity in access to pain management in Brazil.Cadernos de saude publica · 2026Article
- Prevalence and predictors of analgesic use during early pregnancy in a Brazilian population.Frontiers in pharmacology · 2026Article
- A time-series analysis of the use of opioid medications in a network of Brazilian hospitals, 2009-2020.Lancet regional health. Americas · 2025Article
- Self-medication with NSAIDs and purchase of branded and over-the-counter medicines: Analysis of a national survey in Peru.Journal of public health research · 2025Article
- Excessive Self-Medication with Prescription NSAIDs: A Cross-Sectional Study in Kosovo.Pharmacy (Basel, Switzerland) · 2024Article
- Patterns of Opioid and Non-Opioid Analgesic Consumption in Patients with Post-COVID-19 Conditions.Journal of clinical medicine · 2023Article
- Dental Pain Medication Prescriptions in Minas Gerais, Brazil (2011-2021): A Time-Series Analysis.International journal of environmental research and public health · 2023Article
- Prevalence of pain and use of prescription opioids among older adults: results from the Brazilian Longitudinal Study of Aging (ELSI-Brazil).Lancet regional health. Americas · 2023Article
- Self-Medication Profile of Adult Patients with Temporomandibular Disorders in Southeast Brazil.Iranian journal of public health · 2022Article
- Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients.Einstein (Sao Paulo, Brazil) · 2022Article
- Genotoxic and cytotoxic effects of the drug dipyrone sodium in African green monkey kidney (Vero) cell line exposed in vitro.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Opioid use, regulation, and harms in Brazil: a comprehensive narrative overview of available data and indicators.Substance abuse treatment, prevention, and policy · 2021Review
- Predictors of the use of analgesic drugs 1 year after joint replacement: a single-center analysis of 13,000 hip and knee replacements.Arthritis research & therapy · 2020Article
- Exploring the Impact of the Rational Antibiotic Use System on Hospital Performance: The Direct Effect and the Spillover Effect.International journal of environmental research and public health · 2019Article
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- Evaluation of prescription pattern of analgesic use among ambulatory elderly in South-Western Nigeria.Annals of African medicineArticle
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo estimate the prevalence of use of analgesics in Brazil; and to characterize this use, according to sociodemographic and health-related characteristics.
methodsA cross-sectional population-based study (National Survey on Access, Use and Promotion of Rational Use of Medicines, PNAUM) was conducted between September 2013 and February 2014. A total of 41,433 people of all ages in Brazilian urban households were interviewed. Occasional use (within the last 15 days) and continuous use of non-opioid analgesics, opioid analgesics and non-steroidal anti-inflammatory drugs were investigated, regardless of whether this use occurred through prescription or self-medication. The main outcome was the use of at least one analgesic.
resultsThe majority of the individuals were female (52.8%), aged between 20 and 59 years (57.2%), with 1 to 8 years of schooling (45.6%). The overall prevalence of analgesic use was 22.8% [95% CI: 21.4-24.2]. The use of analgesics was significantly higher among women, adults and elderly (20 years or more), highly educated individuals and respondents who referred: diagnosis of one or more chronic diseases, using three or more medications, possession of health insurance and with one or more emergency care admittances or hospitalizations within the last year. Non-opioid analgesics were the agents most used (18.5% of the sample), followed by non-steroidal anti-inflammatory drugs (6.9%) and opioid analgesics (0.5%). The most commonly used drugs were metamizole (37.8% of all analgesics), paracetamol (25.3%) and diclofenac (10.7%). These drugs were used mainly to manage occasional health conditions, particularly pain.
conclusionOne in five Brazilians used some analgesic, especially non-opioid analgesics, to manage acute health problems such as painful conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.