Evidence map›Paper›PMID 30896784›Full record

ReviewInternational journal of oncology2019

Human papillomavirus infection and ocular surface disease (Review).

Aikaterini K Chalkia, Georgios Bontzos, Demetrios A Spandidos, Efstathios T Detorakis

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Review
  5. Article
  6. Article
  7. The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  8. Infectious etiologies of conjunctival tumors.Expert review of ophthalmology · 2025
    Article
  9. Etiologies of Infectious Keratitis in Malawi.The American journal of tropical medicine and hygiene · 2024
    Article
  10. Article
  11. Article
  12. Update in ocular surface squamous neoplasia.Revista da Associacao Medica Brasileira (1992) · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. A man with an ocular mass.Journal of the American College of Emergency Physicians open · 2022
    Article
  18. Article
  19. Article
  20. Association between HPV detection in swab samples and tissue specimens and ophthalmic pterygium recurrence.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Aikaterini K ChalkiaDepartment of Ophthalmology, University Hospital of Heraklion, 71110 Heraklion, Greece.
Georgios BontzosDepartment of Ophthalmology, Red Cross Hospital, 11526 Athens, Greece.
Demetrios A SpandidosDepartment of Virology, Medical School, University of Crete, 71110 Heraklion, Greece.
Efstathios T DetorakisDepartment of Ophthalmology, University Hospital of Heraklion, 71110 Heraklion, Greece.
University Hospital of Heraklion · GRHellenic Red Cross · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) infection has been implicated as a primary cause of lesions in the anogenital region, skin, oropharynx and respiratory tract. Additionally, the role of HPV in the pathogenesis of ocular surface disease has also been extensively studied. Conjunctival papilloma development has been strongly associated with the HPV infection of certain subtypes. On the other hand, the role of HPV in conjunctival pterygium, conjunctival intraepithelial neoplasia (CIN) and ocular surface squamous neoplasia (OSSN) remains controversial. Genetic predisposition and environmental factor is important in HPV hosts as regards the pathogenesis of ocular surface disease. Several studies have indicate a synergic role of HPV with ultraviolet radiation in pterygium establishment. A higher recurrence risk rate and more aggressive disease of ophthalmic pterygium is observed in cases of HPV infection. The purpose of this review was to provide a systematic review of the literature and to assist in a better understanding of the role of HPV in ocular surface disease.

Indexed as

Carcinoma in SituCarcinoma, Squamous CellConjunctivaConjunctival NeoplasmsEye NeoplasmsHumansPapillomavirus InfectionsPterygium

Identifiers

PMID30896784
PMCPMC6438422
OpenAlexW2925189784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.