Evidence map›Paper›PMID 30896660›Full record

Observational studyMedicine2019

Influence of vertebral bone mineral density on total dispersion volume of bone cement in vertebroplasty.

Jun Liu, Zhenghua Liu, Jing Luo, Liqun Gong, Yaqing Cui, Qichun Song, Pei Fen Xiao, Yongchun Zhou

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jun LiuDepartment of Orthopedic, Shaanxi Provincial People's Hospital.
Zhenghua LiuDepartment of Radiology.
Jing LuoDepartments of Nursing Administration, Honghui Hospital, Xi'an Jiaotong University College of Medicine.
Liqun GongDepartment of Orthopedic, Shaanxi Provincial People's Hospital.
Yaqing CuiDepartment of Surgery Center, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, People's Republic of China.
Qichun SongDepartment of Orthopedic, Shaanxi Provincial People's Hospital.
Pei Fen XiaoDepartment of Orthopedic, Shaanxi Provincial People's Hospital.
Yongchun ZhouDepartment of Orthopedic, Shaanxi Provincial People's Hospital.
Shaanxi Provincial People's Hospital · CNXi'an Honghui Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the influence of vertebral bone mineral density (BMD) on total diffusion volume of bone cement in percutaneous vertebroplasty (PVP). This study was a retrospective review of prospectively collected data of consecutive patients with A1.2 thoracolumbar compression fractures treated by PVP. Vertebral BMD was measured before surgery and participants were divided into 3 groups according to World Health Organization diagnostic criteria for osteoporosis: Group A (normal BMD), Group B (reduced BMD), and Group C (osteoporosis). All vertebrae were injected with 3 mL of bone cement via the unilateral pedicle and scanned by computed tomography after surgery. Actual injection volume (bone cement only) and total diffusion volume (bone cement plus trabeculae and space) were calculated. Pain severity was determined by the visual analog scale before surgery and at both 1 day and 1 month after surgery. There were no significant differences in injection volume among the groups (P > .05), but the total dispersion volume was greater than injection volume in all groups (P < .05). Pairwise comparison showed a significant difference in total diffusion volume of bone cement between groups, with Group A having the largest volume and Group C the smallest volume. Pain was significantly reduced 1 day after surgery in each group compared with before surgery, but there were no significant between-group differences at 1 day or 1 month. Increasing vertebral BMD was positively correlated with increasing total diffusion volume. BMD does not significantly affect pain relief, despite producing a significantly lower distribution volume in osteoporotic patients.

Indexed as

AgedAged, 80 and overBone CementsBone DensityFemaleFractures, CompressionHumansLumbar VertebraeMaleMiddle AgedOsteoporosisPain MeasurementRetrospective StudiesSeverity of Illness IndexSpinal FracturesThoracic VertebraeBone Cements

Identifiers

PMID30896660
PMCPMC6709149
OpenAlexW2924358414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.