Evidence map›Paper›PMID 30896347›Full record

ArticleEmerging microbes & infections2019

Evolution and transmission of a conjugative plasmid encoding both ciprofloxacin and ceftriaxone resistance in Salmonella.

Kaichao Chen, Edward Wai Chi Chan, Sheng Chen

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Genomic and resistome analysis ofOne health (Amsterdam, Netherlands) · 2025
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  11. ISMicrobiology spectrum · 2021
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  12. Article
  13. A Multidrug-ResistantMicrobial drug resistance (Larchmont, N.Y.) · 2021
    Article
  14. Delineation of ISFrontiers in microbiology · 2021
    Article
  15. Multiple-Replicon Resistance Plasmids ofFrontiers in microbiology · 2021
    Article
  16. Article
  17. Emergence of 16S rRNA Methylase GeneFrontiers in microbiology · 2020
    Article
  18. Article
  19. Transmission of ciprofloxacin resistance inEmerging microbes & infections · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kaichao Chena Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute , Shenzhen , People's Republic of China.
Edward Wai Chi Chana Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute , Shenzhen , People's Republic of China.
Sheng Chena Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute , Shenzhen , People's Republic of China.
Center for Food Safety and Applied Nutrition · USHong Kong Polytechnic University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftriaxone and ciprofloxacin are the drugs of choice in treatment of invasive Salmonella infections. This study discovered a novel type of plasmid, pSa44-CIP-CRO, which was recovered from a S. London strain isolated from meat product and comprised genetic determinants that encoded resistance to both ciprofloxacin and ceftriaxone. This plasmid could be resolved into two daughter plasmids and co-exist with such daughter plasmids in a dynamic form in Salmonella; yet it was only present as a single plasmid in Escherichia coli. One daughter plasmid, pSa44-CRO, was found to carry the bla

Indexed as

Drug Resistance, BacterialPlasmidsAnimalsAnti-Bacterial AgentsCeftriaxoneCiprofloxacinDisease Models, AnimalEscherichia coliGenes, BacterialMeat ProductsMiceRecombination, GeneticSalmonellaSalmonella InfectionsTreatment FailureAnti-Bacterial AgentsCeftriaxoneCiprofloxacinceftriaxone resistanceciprofloxacin resistanceconjugative plasmidPMQR genesSalmonella

Identifiers

PMID30896347
PMCPMC6455229
OpenAlexW2924420496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.