ArticleMarine biotechnology (New York, N.Y.)2019
Hydrogenation of Halogenated 2'-Hydroxychalcones by Mycelia of Marine-Derived Fungus Penicillium raistrickii.
Article in Marine biotechnology (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Dihydrochalcones: Methods of Acquisition and Pharmacological Properties-A First Systematic Review.Molecules (Basel, Switzerland) · 2019Pooled it
- Marine-derived fungi as biocatalysts.Frontiers in microbiology · 2023Review
- Regiospecific Hydrogenation of Bromochalcone by Unconventional Yeast Strains.Molecules (Basel, Switzerland) · 2022Article
- The Family Keeps on Growing: Four Novel Fungal OYEs Characterized.International journal of molecular sciences · 2022Article
- Biotransformation of Ethinylestradiol by Whole Cells of Brazilian Marine-Derived Fungus Penicillium oxalicum CBMAI 1996.Marine biotechnology (New York, N.Y.) · 2020Article
- Synthesis of Knoevenagel Adducts Under Microwave Irradiation and Biocatalytic Ene-Reduction by the Marine-Derived Fungus Cladosporium sp. CBMAI 1237 for the Production of 2-Cyano-3-Phenylpropanamide Derivatives.Marine biotechnology (New York, N.Y.) · 2020Article
- Effective Hydrogenation of 3-(2"-furyl)- and 3-(2"-thienyl)-1-(2'-hydroxyphenyl)-prop-2-en-1-one in Selected Yeast Cultures.Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study describes the chemoselective hydrogenation reaction of halogenated 2'-hydroxychalcones by the marine-derived fungus Penicillium raistrickii CBMAI 931. Initially, 2'-hydroxychalcone was utilized as a model for the selection of the appropriate conditions to perform the biotransformation reactions. The best results were obtained using mycelia and filtered culture broth, and this condition was chosen for the biotransformation reaction of 2'-hydroxychalcones substituted with methoxy and halogen groups. Experiments performed with 2'-hydroxychalcones dissolved in 600 μL-DMSO were more effective than those performed using 300 μL-DMSO, once solubility of the compounds influenced conversion rate in the liquid medium. The halogenated 2'-hydroxy-dihydrochalcones were obtained in good conversions (78-99%) and moderate isolated yields (31-65%). All biotransformation reactions using the marine-derived fungus P. raistrickii CBMAI 931 showed regioselective and chemoselective control for the formation of 2'-hydroxy-dihydrochalcones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.