Evidence map›Paper›PMID 30895253›Full record

ArticleHuman reproduction open2018

Peripartum and postpartum outcomes in uncomplicated term pregnancy following ART: a retrospective cohort study from two Italian obstetric units.

Silvia Vannuccini, Chiara Ferrata, Federica Perelli, Serena Pinzauti, Filiberto M Severi, Fernando M Reis, Felice Petraglia, Mariarosaria Di Tommaso

Open access · goldAbstract read
In one paragraph

Article in Human reproduction open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Silvia VannucciniObstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, 'S. Maria alle Scotte' University Hospital, viale Bracci, Siena, Italy.
Chiara FerrataDepartment of Health Sciences, University of Florence, Careggi University Hospital, Largo Brambilla, Florence, Italy.
Federica PerelliDepartment of Health Sciences, University of Florence, Careggi University Hospital, Largo Brambilla, Florence, Italy.
Serena PinzautiDepartment of Health Sciences, University of Florence, Careggi University Hospital, Largo Brambilla, Florence, Italy.
Filiberto M SeveriObstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, 'S. Maria alle Scotte' University Hospital, viale Bracci, Siena, Italy.
Fernando M ReisObstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, 'S. Maria alle Scotte' University Hospital, viale Bracci, Siena, Italy.
Felice PetragliaDepartment of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, Careggi University Hospital, Largo Brambilla, Florence, Italy.ORCID 0000-0002-8851-625X
Mariarosaria Di TommasoDepartment of Health Sciences, University of Florence, Careggi University Hospital, Largo Brambilla, Florence, Italy.
University of Florence · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

study questionDo singleton uncomplicated term pregnancies conceived by assisted reproductive technology (ART) have adverse peripartum and postpartum outcomes? SUMMARY ANSWER: Term pregnancies following ART, even if uncomplicated until birth, have a higher risk of retained placenta and postpartum hemorrhage (PPH). WHAT IS KNOWN ALREADY: There is consistent evidence that pregnancies following ART have higher incidence of complications during pregnancy. However, few studies specifically investigated birth outcomes in ART term pregnancies. STUDY DESIGN SIZE DURATION: A retrospective cohort study was conducted on 14 415 deliveries at two university tertiary care obstetric units. Clinical data were extracted by reviewing obstetric records of all deliveries from 1 January 2010 to 31 December 2014, in a standardized electronic database regarding the mother's health before and during pregnancy, complications during pregnancy and at birth, and neonatal outcome. PARTICIPANTS/MATERIALS SETTING

methodsFollowing an accurate evaluation of exclusion criteria (multiparity, maternal pre-pregnancy diseases, prior uterine surgery, fetal malformations, intrauterine deaths, elective cesarean section and pregnancy complications), the group of uncomplicated singleton term pregnancies from autologous ART conception by MAIN RESULTS AND THE ROLE OF CHANCE: The age of women in the final analysis ranged from 25 to 45 years, while BMI ranged from 17 to 34 kg/m LIMITATIONS REASONS FOR CAUTION: The database lacked specific information about causes of infertility, smoking habit, family income and details on ART (fresh versus frozen cycle, IVF versus ICSI), limiting, in part, our analysis of the results. However, only autologous IVF/ICSI pregnancies were included in order to prevent bias related to conception by oocyte/embryo donation. WIDER IMPLICATIONS OF THE

findingsPregnancies conceived by autologous ART that proceed uncomplicated until term may require counseling about the risk of placental retention with PPH. STUDY FUNDING/COMPETING INTERESTS: The authors have no conflict of interest and funding to declare.

Indexed as

ARTdeliveryinduction of laborinfertilityIVFneonatal outcomeoperative deliverypostpartum hemorrhageretained placentauncomplicated pregnancy

Identifiers

PMID30895253
PMCPMC6276695
OpenAlexW2884951349

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.