Blastocyst culture in the Era of PGS and FreezeAlls: Is a 'C' a failing grade?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed.

1. Pregnancy and neonatal outcomes of blastocysts without blastocoele re-expansion in FET patients: are they of clinical value?Journal of assisted reproduction and genetics · 2025
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2. The role of mitochondrial DNA copy number in spent culture medium in predicting outcomes of single blastocyst transfer.Journal of assisted reproduction and genetics · 2025
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3. The Istanbul consensus update: a revised ESHRE/ALPHA consensus on oocyte and embryo static and dynamic morphological assessment†,‡.Human reproduction (Oxford, England) · 2025
   Article
4. Intraovarian platelet-rich plasma injection significantly improves blastocyst yield and quality in IVF patients.Scientific reports · 2025
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5. Assessing the clinical value of day 7 blastocysts: a predictive model for preimplantation genetic testing for aneuploidy (PGT-A) cycles.Journal of assisted reproduction and genetics · 2025
   Article
6. Does cleavage stage morphology increase the discriminatory power of prediction in blastocyst transfer outcome?Journal of assisted reproduction and genetics · 2024
   Article
7. Steady morphokinetic progression is an independent predictor of live birth: a descriptive reference for euploid embryos.Human reproduction open · 2024
   Article
8. Blastocyst quality and reproductive and perinatal outcomes: a multinational multicentre observational study.Human reproduction (Oxford, England) · 2023
   Observational
9. Morphometric assessment of blastocysts: relationship with the ongoing pregnancy rate.F&S reports · 2023
   Article
10. Towards Automation in IVF: Pre-Clinical Validation of a Deep Learning-Based Embryo Grading System during PGT-A Cycles.Journal of clinical medicine · 2023
    Article
11. LC-MS Analysis Revealed the Significantly Different Metabolic Profiles in Spent Culture Media of Human Embryos with Distinct Morphology, Karyotype and Implantation Outcomes.International journal of molecular sciences · 2022
    Article
12. Biphasic (5-2%) oxygen concentration strategy significantly improves the usable blastocyst and cumulative live birth rates in in vitro fertilization.Scientific reports · 2021
    Observational
13. When embryology meets genetics: the definition of developmentally incompetent preimplantation embryos (DIPE)-the consensus of two Italian scientific societies.Journal of assisted reproduction and genetics · 2021
    Article
14. Pregnancy and neonatal outcomes of morphologically grade CC blastocysts: are they of clinical value?Archives of gynecology and obstetrics · 2020
    Article
15. All Models Are Wrong, but Some Are Useful.Journal of assisted reproduction and genetics · 2020
    Article
16. Blastocyst score, a blastocyst quality ranking tool, is a predictor of blastocyst ploidy and implantation potential.F&S reports · 2020
    Article
17. Do patient factors influence embryologists' decisions to freeze borderline blastocysts?Journal of assisted reproduction and genetics · 2020
    Article
18. The Valuable Reference of Live Birth Rate in the Single Vitrified-Warmed BB/BC/CB Blastocyst Transfer: The Cleavage-Stage Embryo Quality and Embryo Development Speed.Frontiers in physiology · 2020
    Article
19. Impact of Day 7 Blastocyst Transfer on Obstetric and Perinatal Outcome of Singletons Born After Vitrified-Warmed Embryo Transfer.Frontiers in physiology · 2020
    Article

Corrections and comments

• Commented on by
  The Vienna consensus: report of an expert meeting on the development of art laboratory performance indicators.2017

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.