Evidence map›Paper›PMID 30895112›Full record

ArticleJournal of dental sciences2018

Antifungal effect of tissue conditioners containing poly(acryloyloxyethyltrimethyl ammonium chloride)-grafted chitosan on

Hsin-Lin Lee, Ren-Syue Wang, Yung-Chuang Hsu, Chuan-Chung Chuang, Hui-Rong Chan, Hsien-Chung Chiu, Yi-Bing Wang, Kuo-Yu Chen, Earl Fu

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Antiparasitic Activity ofVeterinary sciences · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Nanoparticles in Prosthetic Materials: A Literature Review.Journal of pharmacy & bioallied sciences · 2021
    Review
  11. Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Applying the Host-Microbe Damage Response Framework toJournal of fungi (Basel, Switzerland) · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hsin-Lin LeeDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Ren-Syue WangDepartment of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin, Taiwan.
Yung-Chuang HsuDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Chuan-Chung ChuangDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Hui-Rong ChanDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Hsien-Chung ChiuDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Yi-Bing WangDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Kuo-Yu ChenDepartment of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin, Taiwan.
Earl FuDepartment of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Tri-Service General Hospital · TWNational Defense Medical Center · TWNational Yunlin University of Science and Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeDenture stomatitis is a pathological condition affecting the mucosa underneath ill-fitting dentures, and MATERIALS AND

methodsTissue conditioners containing varying weight percentages of CS or QCS were prepared as experimental discs 10 mm in diameter and 1 mm in thickness. Samples were co-cultured with

resultsIt was found significantly fewer fungal colonies in tissue conditioners modified with CS or QCS, and none when the weight percentage of QCS exceeded 5%. CS and QCS did not affect the viability of human gingival epithelium cells or fibroblasts, and tensile bond strength did not differ between control and modified tissue conditioners.

conclusionThis study provides a foundation for the development of QCS as a novel and safe antifungal agent applied to tissue conditioners in clinical practice.

Indexed as

chitosandenture stomatitisquaternizationtissue conditioner

Identifiers

PMID30895112
PMCPMC6388835
OpenAlexW2793537235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.