Evidence map›Paper›PMID 30895091›Full record

ArticleJournal of dental sciences2018

Nicotine is a risk factor for dental caries: An

Shiyu Liu, Tianmu Wu, Xuedong Zhou, Bo Zhang, Sibei Huo, Yutao Yang, Keke Zhang, Lei Cheng, Xin Xu, Mingyun Li

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Effect of Cigarette and E-Cigarette Smoke Condensates onInternational journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Effect of nicotine on biofilm formation ofJournal of oral microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shiyu LiuState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Tianmu WuState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Xuedong ZhouState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Bo ZhangDepartment of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Sibei HuoDepartment of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yutao YangDepartment of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Keke ZhangState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Lei ChengState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Xin XuState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Mingyun LiState Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeMATERIALS AND

methodsSixteen male Specific-pathogen-free Wistar rats were divided into 2 groups (nicotine-treated and nicotine-untreated group) and infected with

resultsIncidence of sulcal caries was higher in nicotine-treated group compared to nicotine-untreated group (42.7 ± 1.7 vs 37.3 ± 4.9, P = 0.009). Severity of caries increased with nicotine treatment. The slightly dentinal caries scores and moderate dentinal caries scores were higher in the presence of nicotine (P < 0.001). Increased number of

conclusionNicotine would promote the attachment of

Indexed as

Dental cariesNicotineRatsStreptococcus mutans

Identifiers

PMID30895091
PMCPMC6388820
OpenAlexW2786167291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.