ArticleJournal of dental sciences2017
S100 protein-positive Langerhans cells in 80 dentigerous cysts.
Article in Journal of dental sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- The Tilapia Cyst Tissue Enclosing the ProliferatingInternational journal of molecular sciences · 2024Article
- Oral giant cell fibroma: A report of three cases.Journal of dental sciences · 2021Article
- Marking vertebrates langerhans cells, from fish to mammals.Acta histochemica · 2020Review
- Cicatricial pemphigoid presenting as desquamative gingivitis.Journal of dental sciences · 2020Article
- Stafne bone defect of the molar region of the mandible.Journal of dental sciences · 2019Article
- Hindrance of tooth eruption and orthodontic tooth movement by focal idiopathic osteosclerosis in the mandible.Journal of dental sciences · 2019Article
- Huge lipoma in the left submandibular region.Journal of dental sciences · 2019Article
- Lymphoepithelial cyst of the tongue.Journal of dental sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeLangerhans cells (LCs) are antigen-presenting cells. This study assessed the LC counts in 80 dentigerous cysts (DCs). MATERIALS AND
methodsThe S100-positive LC numbers in the lining epithelia and subepithelial connective tissues were counted at 80 DC sites without inflammation, 33 DC sites with mild/moderate inflammation, and 9 DC sites with severe inflammation from 80 DC specimens.
resultsThe mean S100-positive LC counts in the lining epithelia and subepithelial connective tissues increased significantly from no inflammation (0.6 ± 0.6 and 0.7 ± 0.6 cell/high-power field or HPF, respectively) through mild/moderate inflammation (8.1 ± 2.0 and 4.5 ± 2.3 cells/HPF, respectively) to severe inflammation DC sites (21.0 ± 7.0 and 11.1 ± 6.5 cells/HPF, respectively;
conclusionA significant association of high-grade inflammation and thick lining epithelium with the increased LC number in DCs is found. Very few LCs in the lining epithelia of DCs without inflammation indicate the reduced immunosurveillance ability against DC lining epithelial cells in DC patients. It needs further studies to confirm the role of reduced immunosurveillance in the enlargement of the DC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.