Evidence map›Paper›PMID 30895001›Full record

ArticleJournal of dental sciences2016

Injectable adipose tissue combined with stem cells for soft-tissue augmentation: A pilot study for dental applications.

Li-Ting Li, Kuang-Ta Yao, Shou-Cheng Teng, Tiffany P Sun, Ching-Kuo Chen, Chia-Chun Chen, Ming-Lun Hsu, Hsu-Wei Fang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Li-Ting LiDepartment of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
Kuang-Ta YaoDepartment of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Shou-Cheng TengDepartment of Plastic and Reconstructive Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Tiffany P SunThomas Jefferson High School for Science and Technology, Alexandria, VA, USA.
Ching-Kuo ChenDepartment of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
Chia-Chun ChenDepartment of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
Ming-Lun HsuSchool of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Hsu-Wei FangDepartment of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
National Taipei University of Technology · TWNational Health Research Institutes · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming University Hospital · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeBone resorption and soft-tissue defects are the typical physiologic responses after tooth extraction. Various dental ridge augmentation techniques have been applied and lack of the soft tissue is the major factor causing the failure. We propose that the adipose-derived stem cell can be useful in soft-tissue augmentation in dental applications. The objective of this study was to optimize the operation procedures for the isolation of adipose stem cells and tissues. Accelerated clinical protocols for effective transplantation of adipose tissue with high amount of adipose stem cells shall be developed. MATERIALS AND

methodsOperation parameters were designed and optimized for the extraction of adipose tissue-derived stromal vascular cells. The optimized accelerated procedure was washing the lipoaspirate samples one time. Collagenase was then added and samples were incubated in a water bath for 30 minutes at 37°C and centrifuged at 1200

resultsThe animal model tests demonstrated the filling and regeneration of the soft tissues with significant angiogenesis.

conclusionThis pilot study demonstrated the feasibility of soft-tissue augmentation applications.

Indexed as

adipose-derived stem cellsalveolar bone resorptioncell-assisted lipotransferridge defectsstromal vascular fraction cells

Identifiers

PMID30895001
PMCPMC6395274
OpenAlexW2460827123

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.