ArticleJournal of dental sciences2016
Co-operative effect of exogenous dextranase and sodium fluoride on multispecies biofilms.
Article in Journal of dental sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Effect of mutanase and dextranase on biofilms of cariogenic bacteria: A systematic review ofBiofilm · 2024Review
- Review on recent advances in the properties, production and applications of microbial dextranases.World journal of microbiology & biotechnology · 2023Review
- Purification and characterization of cold-adapted and salt-tolerant dextranase fromFrontiers in microbiology · 2022Article
- Graphene Oxide-Copper Nanocomposites Suppress CariogenicInternational journal of nanomedicine · 2021Article
- Fluoride contributes to the shaping of microbial community in high fluoride groundwater in Qiji County, Yuncheng City, China.Scientific reports · 2019Article
- Purification, Characterization and Degradation Performance of a Novel Dextranase fromInternational journal of molecular sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeThe co-operative effect of exogenous dextranase (Dex) and sodium fluoride (NaF) on MATERIALS AND
methodsA multispecies biofilm of
resultsIn general, biofilms treated with Dex and a little concentration of NaF exhibited a lower biomass, exopolysaccharide production, and viability compared with the control group (P < 0.05). Confocal laser scanning microscopy using a vital fluorescence technique showed the combination treated biofilms appeared to be loose relatively and single cells could be observed. Furthermore, the thickness and viability were also lower than either of the separate agent groups (P < 0.05).
conclusionOverall, these findings reveal that a combination of 1 U/mL Dex and 80 μg/mL NaF is a promising candidate for disrupting complex cariogenic multispecies biofilms. This feature may be in that Dex loses the structure of biofilms, thereby facilitating NaF penetration and enhancing its antibacterial effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.