Evidence map›Paper›PMID 30894906›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Dimensional Analysis of CD44

Betty Tan, Mpu Kanoko, Gino Tan, Adang Bachtiar, Delfitri Munir

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Betty TanDepartment of Anatomic Pathology of Medical Faculty, University of Sumatera Utara, Jl. Dr Mansyur No 5, Medan 20155, Indonesia.
Mpu KanokoDepartment of Anatomic Pathology of Medical Faculty, University of Indonesia, Jakarta, Indonesia.
Gino TanDepartment of Clinical Pathology of Medical Faculty, University of Sumatera Utara, Medan, Indonesia.
Adang BachtiarFaculty of Public Health, University of Indonesia, Jakarta, Indonesia.
Delfitri MunirDepartment of Otorhinolaryngology of Medical Faculty, University of Sumatera Utara, Medan, Indonesia.
University of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the dimensional analysis CD44

methodsThis cross-sectional study was performed on patients with breast cancer in Haji Adam Malik Hospital Medan from 2013 to 2016 to determine the frequency and pathologic features of TNBC by immunohistochemistry stained.

resultsBy using immunohistochemistry staining panel of CD44, CD24, Twist, Claudin 7, CK5, CK8/18, EMA, E-Cadherin, Ki-67, a total 67 breast tumour samples with TNBC were classified as 9 stem-cells like 1 basal, 22 baso-luminal, and 23 luminal subtypes.

conclusionBy using immunohistochemical staining panel, TNBC can be differentiated into stem cells like basal, baso-luminal and luminal subtypes. Didifferentiation and EMT can produce heterogeneity in TNBC subtypes and this will affect in handling TNBC. Stemness in stem cells- like subtypes are resistant to therapy. Therefore, TNBC needs special attention in order to assist in more optimal handling.

Indexed as

CD24CD44DifferentiationEMTStemnessTriple-negative breast cancer

Identifiers

PMID30894906
PMCPMC6420956
OpenAlexW2920577270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.