Evidence map›Paper›PMID 30894858›Full record

ArticleFrontiers in immunology2019

A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains.

Assunta Liberti, John P Cannon, Gary W Litman, Larry J Dishaw

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Tethering of soluble immune effectors to mucin and chitin reflects a convergent and dynamic role in gut immunity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Assunta LibertiDepartment of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
John P CannonDepartment of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Gary W LitmanDepartment of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Larry J DishawDepartment of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
University of South Florida · USJohns Hopkins University · US

Funding

EVOLUTIONARY ORIGINS OF IMMUNE-TYPE GENESR01AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY WILLIAM · 1985 to 2014
$3.6M
EARLY EVOLUTIONARY ORIGINS OF IMMUNOGLOBULIN GENESR37AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY W · 1995 to 2003
$1.6M
Evolutionary Origins of Immune-Type GenesR56AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY WILLIAM · 2009 to 2009
$77k
NIAID NIH HHS R01 AI023338NIAID NIH HHS R37 AI023338NIAID NIH HHS R56 AI023338
6 · The paper itself

Abstract

The gut microbiome of animals consists of diverse microorganisms that include both prokaryotes and eukaryotes. Complex interactions occur among these inhabitants, as well as with the immune system of the host, and profoundly influence the overall health of both the host and its microbial symbionts. Despite the enormous importance for the host to regulate its gut microbiome, the extent to which animals generate immune-related molecules with the capacity to directly influence polymicrobial interactions remains unclear. The urochordate,

Indexed as

AnimalsBacteriaChitinFluorescent Antibody TechniqueFungiHost-Pathogen InteractionsHumansImmunity, InnateImmunity, MucosalImmunologic FactorsProtein BindingProtein Interaction Domains and MotifsChitinImmunologic FactorsCionafungal-immune interactiongut immunityhost-microorganism interactionsinnate immunitymycobiotatranskingdom interactionsVCBP-C

Identifiers

PMID30894858
PMCPMC6414549
OpenAlexW2922084265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.