Evidence map›Paper›PMID 30894840›Full record

ArticleFrontiers in microbiology2019

High-Throughput Proteomics Identifies Proteins With Importance to Postantibiotic Recovery in Depolarized Persister Cells.

Daniel-Timon Spanka, Anne Konzer, Daniel Edelmann, Bork A Berghoff

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Proteostasis-targeted antibacterial strategies.Journal of microbiology (Seoul, Korea) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Type II Toxin-Antitoxin Systems inInfection and drug resistance · 2025
    Review
  7. Article
  8. Article
  9. Persistence and Culturability ofAntibiotics (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Recent Advances in Bacterial Persistence Mechanisms.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel-Timon SpankaInstitute for Microbiology and Molecular Biology, Justus Liebig University Giessen, Giessen, Germany.
Anne KonzerBiomolecular Mass Spectrometry, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.
Daniel EdelmannInstitute for Microbiology and Molecular Biology, Justus Liebig University Giessen, Giessen, Germany.
Bork A BerghoffInstitute for Microbiology and Molecular Biology, Justus Liebig University Giessen, Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial populations produce phenotypic variants called persisters to survive harmful conditions. Persisters are highly tolerant to antibiotics and repopulate environments after the stress has vanished. In order to resume growth, persisters have to recover from the persistent state, but the processes behind recovery remain mostly elusive. Deciphering these processes is an essential step toward understanding the persister phenomenon in its entirety. High-throughput proteomics by mass spectrometry is a valuable tool to assess persister physiology during any stage of the persister life cycle, and is expected to considerably contribute to our understanding of the recovery process. In the present study, an

Indexed as

antibiotic tolerancedepolarizationpersister cellsproteomicsrecoverySILACTisB toxin

Identifiers

PMID30894840
PMCPMC6414554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.