Evidence map›Paper›PMID 30894787›Full record

ReviewInfectious diseases in obstetrics and gynecology2019

Challenges in the Contemporary Management of Syphilis among Pregnant Women in New Orleans, LA.

Irene A Stafford, Alexandra Berra, Charles G Minard, Virginia Fontenot, Rachel H Kopkin, Eliza Rodrigue, Charles M Roitsch, Martha W Rac, James B Hill

Abstract readReview
In one paragraph

Review in Infectious diseases in obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. State-of-the-Art Review: Congenital Syphilis in the Modern Era: Current Strategies and Future Directions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Syphilis Complicating Pregnancy and Congenital Syphilis.The New England journal of medicine · 2024
    Review
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Irene A StaffordBaylor College of Medicine/Texas Children's Hospital, Department of Obstetrics and Gynecology, Houston, TX, USA.ORCID 0000-0002-2803-7329
Alexandra BerraBaylor College of Medicine/Texas Children's Hospital, Department of Obstetrics and Gynecology, Houston, TX, USA.
Charles G MinardBaylor College of Medicine/Texas Children's Hospital, Institute for Clinical and Translational Research, USA.
Virginia FontenotLouisiana State University Health Sciences Center, Department of Obstetrics and Gynecology, New Orleans, LA, USA.
Rachel H KopkinLouisiana State University Health Sciences Center, Department of Obstetrics and Gynecology, New Orleans, LA, USA.
Eliza RodrigueLouisiana State University Health Sciences Center, Department of Obstetrics and Gynecology, New Orleans, LA, USA.
Charles M RoitschBaylor College of Medicine/Texas Children's Hospital, Section of Neonatology, Houston, TX, USA.
Martha W RacBaylor College of Medicine/Texas Children's Hospital, Department of Obstetrics and Gynecology, Houston, TX, USA.
James B HillBaylor College of Medicine/Texas Children's Hospital, Department of Obstetrics and Gynecology, San Antonio, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this retrospective review is to evaluate trends in the management of maternal and congenital syphilis (CS) in a tertiary care center in New Orleans, LA. Study Design: All cases of maternal and neonatal syphilis over a five year period at Touro Infirmary, New Orleans, LA, were identified using ICD-9/10 codes. Charts were reviewed for demographic and obstetrical variables, stage of syphilis at diagnosis, lab values, and treatment regimen. Newborn treatment and other outcomes were recorded. Results: During the study period 106 infected mother-baby pairs were identified. Of these, 73 charts are available for review. 41% (n = 30) of women received inadequate therapy according to their stage of disease. 9% of newborns (n = 6) were found to be symptomatic for CS; however, only 83.3% of these were admitted to the neonatal intensive care unit. Only 20% (n = 6) of infants were adequately treated with an extended penicillin regimen if the mother was not adequately treated. Furthermore, only 63.0% of newborns had a nontreponemal titer performed. Conclusion: With rising rates of CS, strict adherence to the 2015 CDC guidelines for treatment of syphilis must be maintained.

Indexed as

AdolescentAdultAnti-Bacterial AgentsFemaleHumansInfant, NewbornNew OrleansPenicillinsPregnancyPregnancy Complications, InfectiousRetrospective StudiesSyphilisSyphilis, CongenitalYoung AdultAnti-Bacterial AgentsPenicillins

Identifiers

PMID30894787
PMCPMC6393911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.