ArticleScientific reports2019
Carbon nanotube incorporation in PMMA to prevent microbial adhesion.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Nanoparticle-modified PMMA to prevent denture stomatitis: a systematic review.Archives of microbiology · 2021Pooled it
- Modification of Physico-Chemical and Biological Characteristics of Polymethylmethacrylate with Amorphous Carbon Nanoparticles for Counteracting Healthcare-Associated Infections.Journal of functional biomaterials · 2025Article
- An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications.Journal of advanced research · 2025Review
- Advances in macro-bioactive materials enhancing dentin bonding.Discover nano · 2025Review
- Reinforcing Restorative Dentistry: The Dual Role of Carbon Nanotubes in Material Enhancement and Therapy.International journal of dentistry · 2025Review
- A review on the promising antibacterial agents in bone cement-From past to current insights.Journal of orthopaedic surgery and research · 2024Review
- Assessing the suitability of fused deposition modeling to produce acrylic removable denture bases.Clinical and experimental dental research · 2024Article
- Optical and UV Shielding Properties of Inorganic Nanoparticles Embedded in Polymethyl Methacrylate Nanocomposite Freestanding Films.Polymers · 2024Article
- Nanocomposites Based on Thermoplastic Acrylic Resin with the Addition of Chemically Modified Multi-Walled Carbon Nanotubes.Polymers · 2024Article
- Innovative Nanostructured Fillers for Dental Resins: Nanoporous Alumina and Titania Nanotubes.Biomedicines · 2023Article
- Adhesion of biofilm, surface characteristics, and mechanical properties of antimicrobial denture base resin.The journal of advanced prosthodontics · 2023Article
- The role of nanocomposites against biofilm infections in humans.Frontiers in cellular and infection microbiology · 2023Review
- Polymerization and Applications of Poly(methyl methacrylate)-Graphene Oxide Nanocomposites: A Review.ACS omega · 2022Review
- Anti-Infective and Toxicity Properties of Carbon Based Materials: Graphene and Functionalized Carbon Nanotubes.Microorganisms · 2022Review
- Zinc-modified phosphate-based glass micro-filler improves Candida albicans resistance of auto-polymerized acrylic resin without altering mechanical performance.Scientific reports · 2022Article
- Evaluation of Anti-International journal of molecular sciences · 2022Article
- PMMA-Based Nanocomposites for Odontology Applications: A State-of-the-Art.International journal of molecular sciences · 2022Review
- Mechanical Characterization of Dental Prostheses Manufactured with PMMA-Graphene Composites.Materials (Basel, Switzerland) · 2022Article
- The denture microbiome in health and disease: an exploration of a unique community.Letters in applied microbiology · 2022Review
- Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications.Pharmaceutics · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although PMMA-based biomaterials are widely used in clinics, a major hurdle, namely, their poor antimicrobial (i.e., adhesion) properties, remains and can accelerate infections. In this study, carboxylated multiwalled carbon nanotubes (CNTs) were incorporated into poly(methyl methacrylate) (PMMA) to achieve drug-free antimicrobial adhesion properties. After characterizing the mechanical/surface properties, the anti-adhesive effects against 3 different oral microbial species (Staphylococcus aureus, Streptococcus mutans, and Candida albicans) were determined for roughened and highly polished surfaces using metabolic activity assays and staining for recognizing adherent cells. Carboxylated multiwalled CNTs were fabricated and incorporated into PMMA. Total fracture work was enhanced for composites containing 1 and 2% CNTs, while other mechanical properties were gradually compromised with the increase in the amount of CNTs incorporated. However, the surface roughness and water contact angle increased with increasing CNT incorporation. Significant anti-adhesive effects (35~95%) against 3 different oral microbial species without cytotoxicity to oral keratinocytes were observed for the 1% CNT group compared to the PMMA control group, which was confirmed by microorganism staining. The anti-adhesive mechanism was revealed as a disconnection of sequential microbe chains. The drug-free antimicrobial adhesion properties observed in the CNT-PMMA composite suggest the potential utility of CNT composites as future antimicrobial biomaterials for preventing microbial-induced complications in clinical settings (i.e., Candidiasis).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.