Evidence map›Paper›PMID 30894611›Full record

ArticleScientific reports2019

Orientationally-averaged diffusion-attenuated magnetic resonance signal for locally-anisotropic diffusion.

Magnus Herberthson, Cem Yolcu, Hans Knutsson, Carl-Fredrik Westin, Evren Özarslan

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. NeuroImage · 2021
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Magnus HerberthsonDepartment of Mathematics, Linköping University, Linköping, Sweden. magnus.herberthson@liu.se.
Cem YolcuDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden.ORCID 0000-0002-0722-9161
Hans KnutssonDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden.
Carl-Fredrik WestinDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden.
Evren ÖzarslanDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden.ORCID 0000-0003-0859-1311

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLS, WILLIAM M. · 2012 to 2022
$20.9M
NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

Diffusion-attenuated MR signal for heterogeneous media has been represented as a sum of signals from anisotropic Gaussian sub-domains to the extent that this approximation is permissible. Any effect of macroscopic (global or ensemble) anisotropy in the signal can be removed by averaging the signal values obtained by differently oriented experimental schemes. The resulting average signal is identical to what one would get if the micro-domains are isotropically (e.g., randomly) distributed with respect to orientation, which is the case for "powdered" specimens. We provide exact expressions for the orientationally-averaged signal obtained via general gradient waveforms when the microdomains are characterized by a general diffusion tensor possibly featuring three distinct eigenvalues. This extends earlier results which covered only axisymmetric diffusion as well as measurement tensors. Our results are expected to be useful in not only multidimensional diffusion MR but also solid-state NMR spectroscopy due to the mathematical similarities in the two fields.

Indexed as

Diffusion Magnetic Resonance ImagingAnisotropyHumansModels, TheoreticalWhite Matter

Identifiers

PMID30894611
PMCPMC6426978

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.