ArticleScientific reports2019
Comparison of supine or prone crawl photon or proton breast and regional lymph node radiation therapy including the internal mammary chain.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Reproducibility of repeated breathhold and impact of breathhold failure in whole breast and regional nodal irradiation in prone crawl position.Scientific reports · 2022Trial
- Crawl positioning improves set-up precision and patient comfort in prone whole breast irradiation.Scientific reports · 2020Trial
- Organ at risk sparing by non-coplanar prone breast radiotherapy on Halcyon/Ethos linacs utilizing breast couch slewing.Scientific reports · 2026Article
- Alternative Treatment Positions over Supine in Adjuvant Whole Breast RT: Prone, Lateral or What Else? A Comprehensive Narrative Review.Journal of personalized medicine · 2026Review
- The Prone-Position Whole Breast Irradiation Paradox: Where Do We Stand? A Comprehensive Review.Journal of clinical medicine · 2026Review
- Radiation-induced heart disease in breast cancer patients: a narrative review of epidemiology, risk factors, radiotherapy parameters, and prevention.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Review
- Dosimetric analysis of six whole-breast irradiation techniques in supine and prone positions.Scientific reports · 2024Article
- ESTRO-ACROP guideline for positioning, immobilisation and setup verification for local and loco-regional photon breast cancer irradiation.Technical innovations & patient support in radiation oncology · 2023Article
- Proton therapy for reducing heart and cardiac substructure doses in Indian breast cancer patients.Radiation oncology journal · 2023Article
- Four irradiation and three positioning techniques for whole-breast radiotherapy: Is sophisticated always better?Journal of applied clinical medical physics · 2022Article
- Radiotherapy of Breast Cancer in Laterally Tilted Prone vs. Supine Position: What about the Internal Mammary Chain?Journal of personalized medicine · 2022Article
- Safely achieving single prolonged breath-holds of > 5 minutes for radiotherapy in the prone, front crawl position.The British journal of radiology · 2021Article
- Arms positioning in post-mastectomy proton radiation: Feasibility and development of a new arms down contouring atlas.Physics and imaging in radiation oncology · 2020Article
- Emerging Challenges of Radiation-Associated Cardiovascular Dysfunction (RACVD) in Modern Radiation Oncology: Clinical Practice, Bench Investigation, and Multidisciplinary Care.Frontiers in cardiovascular medicine · 2020Review
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report on a dosimetrical study comparing supine (S) and prone-crawl (P) position for radiotherapy of whole breast (WB) and loco-regional lymph node regions, including the internal mammary chain (LN_IM). Six left sided breast cancer patients were CT-simulated in S and P positions and four patients only in P position. Treatment plans were made using non-coplanar volumetric modulated arc photon therapy (VMAT) or pencil beam scanning intensity modulated proton therapy (IMPT). Dose prescription was 15*2.67 Gy(GyRBE). The average mean heart doses for S or P VMAT were 5.6 or 4.3 Gy, respectively (p = 0.16) and 1.02 or 1.08 GyRBE, respectively for IMPT (p = 0.8; p < 0.001 for IMPT versus VMAT). The average mean lung doses for S or P VMAT were 5.91 or 2.90 Gy, respectively (p = 0.002) and 1.56 or 1.09 GyRBE, respectively for IMPT (p = 0.016). In high-risk patients, average (range) thirty-year mortality rates from radiotherapy-related cardiac injury and lung cancer were estimated at 6.8(5.4-9.4)% or 3.8(2.8-5.1)% for S or P VMAT (p < 0.001), respectively, and 1.6(1.1-2.0)% or 1.2(0.8-1.6)% for S or P IMPT (p = 0.25), respectively. Radiation-related mortality risk could outweigh the ~8% disease-specific survival benefit of WB + LN_IM radiotherapy for S VMAT but not P VMAT. IMPT carries the lowest radiation-related mortality risks.
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