ArticleScientific reports2019
Optimization and evaluation of a non-invasive tool for peste des petits ruminants surveillance and control.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Epidemiology of Peste des Petits Ruminants in Nigeria: A Review.Frontiers in veterinary science · 2022Pooled it
- Strain-dependent differences in the capacity of peste des petits ruminants virus to infect antigen-presenting cells.Journal of virology · 2026Article
- Environmental surveillance: harnessing environmental sample data to protect animal health.Frontiers in veterinary science · 2026Review
- Understanding the host expansion and interspecies infection of peste des petits ruminants virus in view of global control and eradication.Frontiers in cellular and infection microbiology · 2026Article
- Article
- Metagenomic and Molecular Detection of Novel Fecal Viruses in Free-Ranging Agile Wallabies.EcoHealth · 2023Article
- Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance.Diagnostics (Basel, Switzerland) · 2023Article
- Peste Des Petits Ruminants Screening and Diagnostic Tests in African Wildlife in the Context of Rinderpest Eradication (1994-2007).Transboundary and emerging diseases · 2023Article
- The Experimental Infection of Goats with Small Ruminant Morbillivirus Originated from Barbary Sheep.Pathogens (Basel, Switzerland) · 2022Article
- A Review of Non-Invasive Sampling in Wildlife Disease and Health Research: What's New?Animals : an open access journal from MDPI · 2022Review
- Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses.Animals : an open access journal from MDPI · 2021Article
- Wildlife-livestock interactions in animal production systems: what are the biosecurity and health implications?Animal frontiers : the review magazine of animal agriculture · 2021Article
- Peste des Petits Ruminants Virus Infection at the Wildlife-Livestock Interface in the Greater Serengeti Ecosystem, 2015-2019.Viruses · 2021Article
- A systemic approach to assess the potential and risks of wildlife culling for infectious disease control.Communications biology · 2020Review
- Article
- Eradication of Peste des Petits Ruminants Virus and the Wildlife-Livestock Interface.Frontiers in veterinary science · 2020Article
- A Review of the Current Status of Peste des Petits Ruminants Epidemiology in Small Ruminants in Tanzania.Frontiers in veterinary science · 2020Review
- Article
- Article
- Progress to Control and Eradication of Peste des Petits Ruminants in the Southern African Development Community Region.Frontiers in veterinary science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 4 countries.
Funding
Abstract
Peste des petits ruminants (PPR) is a highly contagious and devastating viral disease affecting mainly sheep and goats, but also a large number of wild species within the order Artiodactyla. A better understanding of PPR transmission dynamics in multi-host systems is necessary to efficiently control the disease, in particular where wildlife and livestock co-occur. Notably, the role of wildlife in PPR epidemiology is still not clearly understood. Non-invasive strategies to detect PPR infection without the need for animal handling could greatly facilitate research on PPR epidemiology and management of the disease in atypical hosts and in complex field situations. Here, we describe optimized methods for the direct detection of PPR virus genetic material and antigen in fecal samples. We use these methods to determine the detection window of PPR in fecal samples, and compare the sensitivity of these methods to standard invasive sampling and PPR diagnostic methods using field samples collected at a wildlife-livestock interface in Africa. Our results show that quantitative reverse transcription PCR (RT-QPCR) amplification of PPRV from fecal swabs has good sensitivity in comparison to ocular swabs. Animals infected by PPRV could be identified relatively early on and during the whole course of infection based on fecal samples using RT-QPCR. Partial gene sequences could also be retrieved in some cases, from both fecal and ocular samples, providing important information about virus origin and relatedness to other PPRV strains. Non-invasive strategies for PPRV surveillance could provide important data to fill major gaps in our knowledge of the multi-host PPR epidemiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.