ArticleScientific reports2019
Global Variation of Nutritional Status in Children Undergoing Chronic Peritoneal Dialysis: A Longitudinal Study of the International Pediatric Peritoneal Dialysis Network.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Energy and protein requirements for children with CKD stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2020Guideline
- The impact of nutritional management on the growth and nutritional status of children on regular hemodialysis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Nutritional management of the child with chronic kidney disease and on dialysis.Pediatric nephrology (Berlin, Germany) · 2025Review
- Protein energy wasting in children with chronic kidney disease: is lean body mass by DEXA a key diagnostic biomarker?Pediatric nephrology (Berlin, Germany) · 2024Article
- Role of Nutrients in Pediatric Non-Dialysis Chronic Kidney Disease: From Pathogenesis to Correct Supplementation.Biomedicines · 2024Review
- Diagnosis and management of mineral and bone disorders in infants with CKD: clinical practice points from the ESPN CKD-MBD and Dialysis working groups and the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2023Review
- Malnutrition Patterns in Children with Chronic Kidney Disease.Life (Basel, Switzerland) · 2023Review
- Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2022Review
- Incidence of and risk factors for short stature in children with chronic kidney disease: results from the KNOW-Ped CKD.Pediatric nephrology (Berlin, Germany) · 2021Article
- Longitudinal outcomes of body mass index in overweight and obese children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Targeting optimal PD management in children: what have we learned from the IPPN registry?Pediatric nephrology (Berlin, Germany) · 2021Review
- Enteral Ca-Intake May Be Low and Affects Serum-PTH-Levels in Pre-school Children With Chronic Kidney Disease.Frontiers in pediatrics · 2021Article
- Delivery of a nutritional prescription by enteral tube feeding in children with chronic kidney disease stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2021Review
- Should we abandon GFR in the decision to initiate chronic dialysis?Pediatric nephrology (Berlin, Germany) · 2020Review
- Summary of Expert Opinion on the Management of Children With Chronic Kidney Disease and Growth Failure With Human Growth Hormone.Frontiers in endocrinology · 2020Article
- Determinants of Statural Growth in European Children With Chronic Kidney Disease: Findings From the Cardiovascular Comorbidity in Children With Chronic Kidney Disease (4C) Study.Frontiers in pediatrics · 2019Article
- Not Just Small Adults: Considerations for Pediatric Chronic Kidney Disease.Indian journal of nephrologyReview
- Subjective Global Nutritional Assessment [SGNA] in Children on Chronic Dialysis- A Prospective Observational Study.Indian journal of nephrologyArticle
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Authors and funding
35 authors at 20 institutions in 39 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While children approaching end-stage kidney disease (ESKD) are considered at risk of uremic anorexia and underweight they are also exposed to the global obesity epidemic. We sought to investigate the variation of nutritional status in children undergoing chronic peritoneal dialysis (CPD) around the globe. The distribution and course of body mass index (BMI) standard deviation score over time was examined prospectively in 1001 children and adolescents from 35 countries starting CPD who were followed in the International Pediatric PD Network (IPPN) Registry. The overall prevalence of underweight, and overweight/obesity at start of CPD was 8.9% and 19.7%, respectively. Underweight was most prevalent in South and Southeast Asia (20%), Central Europe (16.7%) and Turkey (15.2%), whereas overweight and obesity were most common in the Middle East (40%) and the US (33%). BMI SDS at PD initiation was associated positively with current eGFR and gastrostomy feeding prior to PD start. Over the course of PD BMI SDS tended to increase on CPD in underweight and normal weight children, whereas it decreased in initially overweight patients. In infancy, mortality risk was amplified by obesity, whereas in older children mortality was markedly increased in association with underweight. Both underweight and overweight are prevalent in pediatric ESKD, with the prevalence varying across the globe. Late dialysis start is associated with underweight, while enteral feeding can lead to obesity. Nutritional abnormalities tend to attenuate with time on dialysis. Mortality risk appears increased with obesity in infants and with underweight in older children.
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