Evidence map›Paper›PMID 30894592›Full record

ArticleScientific reports2019

Identification of new DNA-associated proteins from Waddlia chondrophila.

Marie de Barsy, Lucas Herrgott, Virginie Martin, Trestan Pillonel, Patrick H Viollier, Gilbert Greub

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Amino Acid Composition in Various Types of Nucleic Acid-Binding Proteins.International journal of molecular sciences · 2021
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marie de BarsyInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
Lucas HerrgottInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
Virginie MartinInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
Trestan PillonelInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-5725-7929
Patrick H ViollierDepartment Microbiology and Molecular Medicine, Institute of Genetics & Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Gilbert GreubInstitute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland. gilbert.greub@chuv.ch.ORCID 0000-0001-9529-3317
University of Lausanne · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptional regulation in Chlamydiae is still poorly understood. The absence until recently of genetic tools is the main cause of this gap. We discovered three new potential DNA-associated proteins of Waddlia chondrophila, a Chlamydia-related bacterium, using heparin chromatography coupled to mass spectrometry (Wcw_0377, Wcw_1456, and Wcw_1460). By ChIP-seq analysis, we determined the regulatory landscape of these three proteins and we showed that Wcw_0377 binds all along the genome whereas Wcw_1456 and _1460 possess a wide regulon with a large number of co-regulated genes. Wcw_1456 and Wcw_1460 interact with RpoD (σ

Indexed as

AnimalsBacterial ProteinsChlamydiaceae InfectionsChlamydialesChlorocebus aethiopsDNA-Binding ProteinsHEK293 CellsHumansVero CellsBacterial ProteinsDNA-Binding Proteins

Identifiers

PMID30894592
PMCPMC6426960
OpenAlexW2924650201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.