Evidence map›Paper›PMID 30894434›Full record

ArticlemSphere2019

Outbreak of Murine Infection with

Theresa Mau, Samantha S Eckley, Ingrid L Bergin, Katie Saund, Jason S Villano, Kimberly C Vendrov, Evan S Snitkin, Vincent B Young, Raymond Yung

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Theresa MauDivision of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-4278-6438
Samantha S EckleyUnit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Ingrid L BerginUnit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-5436-4633
Katie SaundDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Jason S VillanoUnit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Kimberly C VendrovDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Evan S SnitkinDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Vincent B YoungDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA youngvi@med.umich.edu ryung@med.umich.edu.ORCID 0000-0003-3687-2364
Raymond YungDivision of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA youngvi@med.umich.edu ryung@med.umich.edu.ORCID 0000-0002-8181-027X
University of Michigan · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Research Training in BiogerontologyT32AG000114 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 1985 to 2026
$12.4M
PREDOCTORAL TRAINING IN GENETICST32GM007544 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORAN, JOHN V. · 1985 to 2022
$11.3M
Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8M
RESEARCH TRAINING IN EXPERIMENTAL IMMUNOPATHOLOGYT32AI007413 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bethany B. Moore · 1993 to 2026
$9.8M
Leukocyte-Endothelial Cell Interaction in AgingR01AG020628 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YUNG, RAYMOND L · 2003 to 2014
$3.2M
Molecular Regulation of CC Chemokine in Atherosclerosis and AgingR01AG028268 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YUNG, RAYMOND L · 2006 to 2010
$1.6M
Leukocyte-endothelial cell interaction in agingR56AG020628 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YUNG, RAYMOND L · 2009 to 2009
$374k
TUMOR INDUCED IMMUNOSUPPRESSIONZ01AG000114 · NIA · AGING · PI LONGO, DAN L. · 2000 to 2007
$241k
Intramural NIH HHS Z01 AG000114NIAID NIH HHS T32 AI007413NIAID NIH HHS U01 AI124255NIA NIH HHS P30 AG024824NIA NIH HHS R01 AG020628NIA NIH HHS R01 AG028268NIA NIH HHS R56 AG020628NIA NIH HHS T32 AG000114NIGMS NIH HHS T32 GM007544
6 · The paper itself

Abstract

Between October 2016 and June 2017, a C57BL/6J mouse colony that was undergoing a pre- and perinatal methyl donor supplementation diet intervention to study the impact of parental nutrition on offspring susceptibility to disease was found to suffer from an epizootic of unexpected deaths. Necropsy revealed the presence of severe colitis, and further investigation linked these outbreak deaths to a

Indexed as

Disease OutbreaksAnimalsBetaineCholineClostridioides difficileClostridium InfectionsDietDietary SupplementsDisease SusceptibilityFemaleMaleMethionineMiceMice, Inbred C57BLParenteral NutritionRibotypingBetaineCholineMethionineClostridium difficilemouseoutbreakveterinary epidemiology

Identifiers

PMID30894434
PMCPMC6429045
OpenAlexW2921152634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.