Evidence map›Paper›PMID 30894429›Full record

ArticlemSphere2019

CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in

Ine Storaker Myrbråten, Kamilla Wiull, Zhian Salehian, Leiv Sigve Håvarstein, Daniel Straume, Geir Mathiesen, Morten Kjos

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Molecular genetic characterization of bacterial KH-domain proteins.bioRxiv : the preprint server for biology · 2026
    Article
  5. Occurrence and applications of CRISPR-Cas systems in bifidobacteria.Applied and environmental microbiology · 2026
    Review
  6. Article
  7. Review
  8. Inactivation of KhpB (EloR/Jag) inApplied and environmental microbiology · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ine Storaker MyrbråtenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Kamilla WiullFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Zhian SalehianFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Leiv Sigve HåvarsteinFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Daniel StraumeFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Geir MathiesenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway geir.mathiesen@nmbu.no morten.kjos@nmbu.no.
Morten KjosFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway geir.mathiesen@nmbu.no morten.kjos@nmbu.no.ORCID 0000-0003-4448-9082
Norwegian University of Life Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies of essential genes in bacteria are often hampered by the lack of accessible genetic tools. This is also the case for

Indexed as

CRISPR-Cas SystemsGenes, cdcGenes, EssentialBacterial ProteinsCell WallDNA ReplicationGene Knockdown TechniquesLactiplantibacillus plantarumPhenotypePlasmidsRNA InterferenceBacterial Proteinsacm2bacterial cell cyclecozECRISPRidnaAeloRezrAkhpAknockdownLactobacillus plantarum

Identifiers

PMID30894429
PMCPMC6429040
OpenAlexW2923622510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.