Observational studyArchives of disease in childhood. Fetal and neonatal edition2019
Neonatal outcomes in preterm multiples receiving delayed cord clamping.
Observational study in Archives of disease in childhood. Fetal and neonatal edition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Hemodynamic effect of delayed cord clamping versus early cord clamping in preterm twins using echocardiography: a prospective observational study.Pediatric research · 2026Article
- Achieving optimal cord management: a multidisciplinary quality improvement initiative.BMJ open quality · 2024Article
- What does the evidence tell us? Revisiting optimal cord management at the time of birth.European journal of pediatrics · 2022Review
- Placental transfusion and short-term outcomes among extremely preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2021Observational
- Germinal Matrix-Intraventricular Hemorrhage: A Tale of Preterm Infants.International journal of pediatrics · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare neonatal outcomes in singletons versus multiples, first-born versus second-born multiples and monochorionic versus dichorionic/trichorionic multiples <33 weeks' gestational age (GA) who received delayed cord clamping (DCC).
designRetrospective, observational study of 529 preterm infants receiving ≥30 s DCC. Generalised estimating equations and mixed effects models were used to compare outcomes in singletons versus multiples and monochorionic versus dichorionic/trichorionic multiples. Wilcoxon signed-rank and McNemar tests were used to compare first-born versus second-born multiples.
settingLevel III neonatal intensive care unit, California, USA. PATIENTS: 433 singletons and 96 multiples <33 weeks' GA, born January 2008-December 2017, who received DCC.
results86% of multiples and 83% of singletons received DCC. Multiples had higher GA (31.0 weeks vs 30.6 weeks), more caesarean sections (91% vs 54%), fewer males (48% vs 62%) and higher 12-24 hour haematocrits (54.3 vs 50.5) than singletons. Haematocrit difference remained significant after adjusting for birth weight, delivery type and sex. Compared with first-born multiples, second-born multiples were smaller (1550 g vs 1438 g) and had lower survival without major morbidity (91% vs 77%). Survival without major morbidity was not significant after adjusting for birth weight. Compared with dichorionic/trichorionic multiples, monochorionic multiples had slightly lower admission temperatures (37.0°C vs 36.8°C), although this difference was not clinically significant. There were no other differences in delivery room, respiratory, haematological or neonatal outcomes between singletons and multiples or between multiples' subgroups.
conclusionsNeonatal outcomes in preterm infants receiving DCC were comparable between singletons and multiples, first and second order multiples and monochorionic and dichorionic/trichorionic multiples.
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