ArticleVirology journal2019
Evaluation of Potato virus X mild mutants for cross protection against severe infection in China.
Article in Virology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Construction and Characterization of an Attenuated Vaccine Vector Based on Cucumber Mosaic Virus RNA2.Life (Basel, Switzerland) · 2026Article
- Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon.Molecular plant pathology · 2026Article
- Generation of a Bivalent Recombinant Vaccine Conferring Dual Protection Against Potyvirus and Orthotospovirus in Cucurbits.Viruses · 2026Article
- Transcriptome Profiling Identifies Key Regulators of Tuber Skin Color in Potato.Plants (Basel, Switzerland) · 2025Article
- Development of an attenuated potato virus Y mutant carrying multiple mutations in helper-component protease for cross-protection.Virus research · 2024Article
- Identification and Characterization of a Novel Quanzhou Mulberry Virus from Mulberry (Viruses · 2023Article
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- Article
- Long-Term Potato Virus X (PVX)-Based Transient Expression of Recombinant GFP Protein inPlants (Basel, Switzerland) · 2021Article
- Development and Evaluation of Stable Sugarcane Mosaic Virus Mild Mutants for Cross-Protection Against Infection by Severe Strain.Frontiers in plant science · 2021Article
- Scientific Opinion on the update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA (2017-2019).EFSA journal. European Food Safety Authority · 2020Article
- Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 11: suitability of taxonomic units notified to EFSA until September 2019.EFSA journal. European Food Safety Authority · 2020Article
- A Spontaneous Complementary Mutation Restores the RNA Silencing Suppression Activity of HC-Pro and the Virulence of Sugarcane Mosaic Virus.Frontiers in plant science · 2020Article
- A New Era for Mild Strain Cross-Protection.Viruses · 2019Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCross protection is a promising alternative to control plant viral diseases. One critical factor limiting the application of cross protection is the availability of attenuated mutants or mild strains. Potato virus X (PVX) infects many crops and induces huge economic losses to agricultural production. However, researches on the variability and mechanism of PVX virulence are scarce.
methodsThe mutants were obtained by introducing mutations into the RNA dependent RNA polymerase (RdRp) gene of PVX via site-directed mutagenesis. Attenuated mutants were screen according to their symptoms in Nicotiana benthamiana plants. The protection efficacy against severe infection were evaluated with interval of 5, 10 and 15 days.
resultsAmong the 40 mutants obtained, four mutants carrying substitutions of either Glu
conclusionMutations of Glu
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Registered trials
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