Evidence map›Paper›PMID 30894126›Full record

ArticleBMC neuroscience2019

Additive effect of 5-HT2C and CB1 receptor blockade on the regulation of sleep-wake cycle.

Emese Bogáthy, Noémi Papp, Laszló Tóthfalusi, Szilvia Vas, György Bagdy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. A Review of the Effects of Adolescent Cannabis Use on Physical Health.The Psychiatric clinics of North America · 2023
    Review
  3. A Review of the Effects of Adolescent Cannabis Use on Physical Health.Child and adolescent psychiatric clinics of North America · 2023
    Review
  4. Article
  5. Frontiers in psychiatry · 2021
    Article
  6. Acute 5-HTFrontiers in pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Emese BogáthyDepartment of Pharmacodynamics, Semmelweis University, Budapest, Nagyvárad tér 4, 1089, Hungary.ORCID 0000-0003-3676-1170
Noémi PappDepartment of Pharmacodynamics, Semmelweis University, Budapest, Nagyvárad tér 4, 1089, Hungary.
Laszló TóthfalusiDepartment of Pharmacodynamics, Semmelweis University, Budapest, Nagyvárad tér 4, 1089, Hungary.
Szilvia VasDepartment of Pharmacodynamics, Semmelweis University, Budapest, Nagyvárad tér 4, 1089, Hungary.
György BagdyDepartment of Pharmacodynamics, Semmelweis University, Budapest, Nagyvárad tér 4, 1089, Hungary. bag13638@iif.hu.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious data show that serotonin 2C (5-HT

resultsWistar rats were equipped with electroencephalography (EEG) and electromyography (EMG) electrodes. Following the recovery and habituation after surgery, animals were injected intraperitoneally (ip.) with SB-242084, a 5-HT

conclusionsOur results suggest that 5-HT

Indexed as

AminopyridinesAnimalsCannabinoid Receptor AntagonistsDrug SynergismElectroencephalographyElectromyographyIndolesMalePiperidinesPyrazolesRats, WistarReceptor, Cannabinoid, CB1Receptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AntagonistsSleepWakefulness6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indolineAM 251AminopyridinesCannabinoid Receptor AntagonistsCnr1 protein, ratIndolesPiperidinesPyrazolesReceptor, Cannabinoid, CB1Receptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AntagonistsWakefulness-Promoting AgentsAM-251Cannabinoid 1 receptorElectroencephalographySB-242084Serotonin 2C receptorSleep

Identifiers

PMID30894126
PMCPMC6427841
OpenAlexW2922723065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.