Evidence map›Paper›PMID 30894090›Full record

ArticleInnate immunity2019

Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia.

Wude Mihret, Berit Sletbakk Brusletto, Reidun Øvstebø, Anne-Marie Siebke Troseid, Gunnstein Norheim, Yared Merid, Afework Kassu, Workeabeba Abebe, Samuel Ayele, Mezgebu Silamsaw Asres and 5 more

Open access · goldAbstract read
In one paragraph

Article in Innate immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Molecular Diagnosis of Bacterial Meningitis in Ethiopia: A Narrative Review of Current Evidence and Implementation Gaps.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Wude Mihret1 Department of Microbial and Cellular Molecular Biology, Addis Ababa University, Ethiopia.
Berit Sletbakk Brusletto3 Department of Clinical Chemistry, Oslo University Hospital, Norway.
Reidun Øvstebø3 Department of Clinical Chemistry, Oslo University Hospital, Norway.
Anne-Marie Siebke Troseid3 Department of Clinical Chemistry, Oslo University Hospital, Norway.
Gunnstein Norheim4 Institute of Public Health, Oslo, Norway.
Yared Merid5 Hawassa University, Ethiopia.
Afework Kassu5 Hawassa University, Ethiopia.
Workeabeba Abebe6 Addis Ababa University, Ethiopia.
Samuel Ayele2 Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Mezgebu Silamsaw Asres7 University of Gondar, Ethiopia.
Lawrence Yamuah2 Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Abraham Aseffa2 Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Beyene Petros6 Addis Ababa University, Ethiopia.
Dominique A Caugant4 Institute of Public Health, Oslo, Norway.
Petter Brandtzaeg3 Department of Clinical Chemistry, Oslo University Hospital, Norway.
Oslo University Hospital · NOAddis Ababa University · ETArmauer Hansen Research Institute · ETHawassa University · ETNorwegian Institute of Public Health · NOUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neisseria meningitidis infections in sub-Saharan Africa usually present with distinct symptoms of meningitis but very rarely as fulminant septicemia when reaching hospitals. In Europe, development of persistent meningococcal shock and multiple organ failure occurs in up to 30% of patients and is associated with a bacterial load of >10

Indexed as

EpidemicsAdolescentAdultAgedChildChild, PreschoolCytokinesDNA, BacterialEthiopiaFemaleHumansInfantInflammation MediatorsMaleMatrix Metalloproteinase 9Meningitis, MeningococcalCytokinesDNA, BacterialInflammation MediatorsMatrix Metalloproteinase 9Bacterial meningitiscerebrospinal fluidchemokinecytokinelipopolysaccharidesmatrix metallopeptidase-9septicemiaseptic shock

Identifiers

PMID30894090
PMCPMC6830936
OpenAlexW2925061883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.