Evidence map›Paper›PMID 30893948›Full record

ArticleJournal of clinical medicine2019

Positive Immuno-Modulation Following Radiofrequency Assisted Liver Resection in Hepatocellular Carcinoma.

Kai Wen Huang, Kumar Jayant, Po-Huang Lee, Po-Chih Yang, Chih-Yang Hsiao, Nagy Habib, Mikael H Sodergren

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  15. Percutaneous Ablation-Induced Immunomodulation in Hepatocellular Carcinoma.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kai Wen HuangDepartment of Surgery & Hepatitis Research Center, National Taiwan University Hospital, Taipei 10051, Taiwan. skyntuh@gmail.com.
Kumar JayantDepartment of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK. jkumar@ic.ac.uk.
Po-Huang LeeDepartment of Surgery & Hepatitis Research Center, National Taiwan University Hospital, Taipei 10051, Taiwan. pohuang111@ntu.edu.tw.
Po-Chih YangGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 10051, Taiwan. youngbirds@gmail.com.
Chih-Yang HsiaoDepartment of Surgery & Hepatitis Research Center, National Taiwan University Hospital, Taipei 10051, Taiwan. cyhsiao1102@gmail.com.
Nagy HabibDepartment of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK. nagy.habib@imperial.ac.uk.
Mikael H SodergrenDepartment of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK. m.sodergren@imperial.ac.uk.
National Taiwan University Hospital · TWImperial College London · GBFu Jen Catholic University · TWThe Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatocellular carcinoma (HCC) often develops on a background of chronic inflammation and a complex immunosuppressive network with increased regulatory T cells, impaired CD8⁺ T cells and the secretion of immunosuppressive cytokines. Previous clinical studies have reported a superior disease-free survival (DFS) following a radiofrequency-based ablation or resection in HCC tumours compared to conventional liver resection techniques. The aim of this study was to investigate whether there is any correlation with the use of a radiofrequency-assisted liver resection and clinical outcome. MATERIAL AND

methodsPatients' peripheral blood was collected prior and 7 days following surgery from patients undergoing a liver resection for HCC. There were 5 liver resections performed using CUSA and 6 liver resections with the RF-based device, Habib

resultsPatients undergoing an RF-assisted liver resection with Habib

conclusionA liver resection with RF-based device Habib

Indexed as

liver cancerliver resectionradiofrequency based device

Identifiers

PMID30893948
PMCPMC6463076
OpenAlexW2924493404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.