ReviewMaterials (Basel, Switzerland)2019
Regenerative Endodontic Procedures Using Contemporary Endodontic Materials.
Review in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 84 citations in OpenAlex.
- Postoperative pain of single-visit endodontic treatment with gutta-percha versus MTA filling: a randomized superiority trial.BMC oral health · 2023Trial
- Regenerative Endodontic Procedure in Mandibular First Molar: A Clinical Case Report.Clinical case reports · 2026Article
- Clinical outcomes and prognostic factors of extended calcium hydroxide medication followed by a bioceramic apical barrier in immature permanent teeth: a retrospective study.BMC oral health · 2026Article
- Establishment of a regenerative endodontic procedures model of mature mouse teeth and evaluation of the wound healing process.Odontology · 2026Article
- Assessment of the dentine microhardness following the application of different intracanal medicaments. An in-vitro study.BDJ open · 2026Article
- Pulp-Dentin Regeneration via Cell Homing: Current Evidence and Perspectives on Cell-Free Regenerative Endodontic Therapy.Medicina (Kaunas, Lithuania) · 2026Review
- Antibiotic approaches to endodontic regeneration.Biomaterial investigations in dentistry · 2026Review
- Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin.Journal of pharmacy & bioallied sciences · 2025Article
- Endodontic bioceramics: current and futurity aspects.Frontiers in oral health · 2025Review
- Conservative Management of Horizontal Root Fracture: A Case Report.Clinical case reports · 2024Article
- Investigation of the cytotoxic effect of current dentine bonding agents on human dental pulp cells.BMC oral health · 2024Article
- Root Canal Dentin Microhardness after Contact with Antibiotic Medications: An In Vitro Study.Dentistry journal · 2024Article
- Advanced Materials for Clinical Endodontic Applications: Current Status and Future Directions.Journal of functional biomaterials · 2024Article
- Mapping global research in dental pulp regeneration: A 10-year bibliometric analysis.Dental research journal · 2024Article
- Can a dentin bonding agent prevent color change in regenerative endodontic procedures? An in vitro evaluation.Brazilian dental journal · 2024Article
- 3D finite element analysis of stress distribution as a result of oblique and horizontal forces after regenerative endodontic treatment part II: comparison of material thickness.BMC oral health · 2023Article
- Evaluation of removal efficiency of capping materials used in pulp revascularization in vitro.BMC oral health · 2023Article
- Bismuth release from endodontic materials: in vivo analysis using Wistar rats.Scientific reports · 2023Article
- Apical Sealing and Bioactivity of an Experimental Gutta-Percha Containing Niobium Phosphate Bioglass.Polymers · 2023Article
- Bioceramics in Endodontics: Updates and Future Perspectives.Bioengineering (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium hydroxide apexification and Mineral Trioxide Aggregate (MTA) apexification are classical treatments for necrotic immature permanent teeth. The first tend to fail for lack of compliance given the high number of sessions needed; the second has technical difficulties such as material manipulation and overfilling. With both techniques, the root development is interrupted leaving the tooth with a fragile root structure, a poor crown-to-root ratio, periodontal breakdown, and high risk of fracture, compromising long-term prognosis of the tooth. New scientific literature has described a procedure that allows complete root development of these specific teeth. This regenerative endodontic procedure (REP) proposes the use of a combination of antimicrobials and irrigants, no canal walls instrumentation, induced apical bleeding to form a blood clot and a tight seal into the root canal to promote healing. MTA is the most used material to perform this seal, but updated guidelines advise the use of other bioactive endodontic cements that incorporate calcium and silicate in their compositions. They share most of their characteristics with MTA but claim to have fewer drawbacks with regards to manipulation and aesthetics. The purpose of the present article is to review pertinent literature and to describe the clinical procedures protocol with its variations, and their clinical application.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.