Evidence map›Paper›PMID 30893785›Full record

ArticleMolecules (Basel, Switzerland)2019

Aspernolide A Inhibits the Proliferation of Human Laryngeal Carcinoma Cells through the Mitochondrial Apoptotic and STAT3 Signaling Pathways.

Chang Liu, Hong Liu, Yanzhang Wen, Huiqi Huang, Ji Hao, Yibing Lv, Rui Qin, Xinzhou Yang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Wound Healing, Metabolite Profiling, and In Silico Studies ofCurrent issues in molecular biology · 2024
    Article
  3. Article
  4. A novel tyrosine tRNA-derived fragment, tRFCellular & molecular biology letters · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chang LiuCollege of Life Sciences, South-Central University for Nationalities, Wuhan 430074, China. liuchang19941129@163.com.ORCID 0000-0002-8945-5786
Hong LiuCollege of Life Sciences, South-Central University for Nationalities, Wuhan 430074, China. 3032307@mail.scuec.edu.cn.
Yanzhang WenSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. 15172435677@163.com.
Huiqi HuangSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. Hhuiqi@hotmail.com.
Ji HaoSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. 13618615220@163.com.
Yibing LvSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. m13525371866@163.com.
Rui QinCollege of Life Sciences, South-Central University for Nationalities, Wuhan 430074, China. 3047807@mail.scuec.edu.cn.
Xinzhou YangSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. xzyang@mail.scuec.edu.cn.
South Central Minzu University · CN

Funding

Applied Basic Research Programs of Science and Technology Commission Foundation of Wuhan No. 2017060201010217Fund for Key Laboratory Construction of Hubei Province No.2018BFC360National Natural Science Foundation of China grant 81774000
6 · The paper itself

Abstract

Aspernolide A, a butyrolactone secondary metabolite, was purified from the endophytic fungus

Indexed as

4-ButyrolactoneApoptosisbcl-2-Associated X ProteinCaspase 3Caspase 9Cell Line, TumorCell ProliferationHumansLaryngeal NeoplasmsMembrane Potential, MitochondrialMitochondriaSignal TransductionSTAT3 Transcription Factor4-Butyrolactoneaspernolide Abcl-2-Associated X ProteinCASP3 protein, humanCaspase 3Caspase 9STAT3 Transcription Factoranticancerapoptosisaspernolide Acamptotheca acuminata decnecladosporium cladosporioideslaryngeal cancermitochondrial pathwaySTAT3

Identifiers

PMID30893785
PMCPMC6471715
OpenAlexW2921668758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.