Evidence map›Paper›PMID 30893771›Full record

ArticleMolecules (Basel, Switzerland)2019

Amyloid-Targeting PET Tracer [

Sanna Hellberg, Johanna M U Silvola, Heidi Liljenbäck, Max Kiugel, Olli Eskola, Harri Hakovirta, Sohvi Hörkkö, Veronique Morisson-Iveson, Ella Hirani, Pekka Saukko and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Automatic lesion detection and segmentation inBiomedical engineering online · 2022
    Article
  4. Review
  5. Review
  6. Novel Tracers and Radionuclides in PET Imaging.Radiologic clinics of North America · 2021
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Sanna HellbergTurku PET Centre, University of Turku, FI-20520 Turku, Finland. sanna.hellberg@utu.fi.ORCID 0000-0003-1791-3693
Johanna M U SilvolaTurku PET Centre, University of Turku, FI-20520 Turku, Finland. johanna.silvola@gmail.com.
Heidi LiljenbäckTurku PET Centre, University of Turku, FI-20520 Turku, Finland. halilj@utu.fi.ORCID 0000-0001-9372-1584
Max KiugelTurku PET Centre, University of Turku, FI-20520 Turku, Finland. max.kiugel@utu.fi.
Olli EskolaTurku PET Centre, University of Turku, FI-20520 Turku, Finland. olli.eskola@utu.fi.
Harri HakovirtaDepartment of Vascular Surgery, Turku University Hospital, FI-20520 Turku, Finland. harri.hakovirta@tyks.fi.ORCID 0000-0002-1518-045X
Sohvi HörkköMedical Research Center and Nordlab Oulu, University Hospital and Research Unit of Biomedicine, Faculty of Medicine, University of Oulu, FI-90014 Oulu, Finland. sohvi.horkko@oulu.fi.
Veronique Morisson-IvesonGE Healthcare Ltd., Chalfont St Giles HP8 4SP, UK. Veronique.MorissonIveson@ge.com.
Ella HiraniGE Healthcare Ltd., Chalfont St Giles HP8 4SP, UK. Ella.Hirani@ge.com.
Pekka SaukkoDepartment of Pathology and Forensic Medicine, University of Turku, FI-20520 Turku, Finland. psaukko@utu.fi.
Seppo Ylä-HerttualaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, FI-70210 Kuopio, Finland. seppo.ylaherttuala@uef.fi.ORCID 0000-0001-7593-2708
Juhani KnuutiTurku PET Centre, University of Turku, FI-20520 Turku, Finland. juhani.knuuti@utu.fi.
Antti SarasteTurku PET Centre, University of Turku, FI-20520 Turku, Finland. antti.saraste@utu.fi.
Anne RoivainenTurku PET Centre, University of Turku, FI-20520 Turku, Finland. anne.roivainen@utu.fi.ORCID 0000-0002-4006-7977
University of Turku · FIOulu University Hospital · FITurku University Hospital · FIUniversity of Eastern Finland · FI

Funding

Ida Montinin Säätiö N/AJane ja Aatos Erkon Säätiö N/ASigrid Juséliuksen Säätiö N/ASuomen Kulttuurirahasto N/ASydäntutkimussäätiö N/ATurku University Foundation N/A
6 · The paper itself

Abstract

Atherosclerosis is characterized by the accumulation of oxidized lipids in the artery wall, which triggers an inflammatory response. Oxidized low-density lipoprotein (ox-LDL) presents amyloid-like structural properties, and different amyloid species have recently been recognized in atherosclerotic plaques. Therefore, we studied the uptake of the amyloid imaging agent [

Indexed as

AnimalsAtherosclerosisAutoradiographyFemaleHumansImmunohistochemistryLipoproteins, LDLMacrophagesMaleMiceMice, Inbred C57BLPlaque, AtheroscleroticPositron Emission Tomography Computed TomographyLipoproteins, LDLoxidized low density lipoproteinamyloidatherosclerosisautoradiographyimagingpositron emission tomography

Identifiers

PMID30893771
PMCPMC6471324
OpenAlexW2922142038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.