Evidence map›Paper›PMID 30893765›Full record

ArticleMarine drugs2019

Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail,

Ai-Hua Jin, Sébastien Dutertre, Mriga Dutt, Vincent Lavergne, Alun Jones, Richard J Lewis, Paul F Alewood

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Molecular Insights into the Marine GastropodInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. In Silico Conotoxin Studies: Progress and Prospects.Molecules (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Review
  11. Comparative Venomics ofMarine drugs · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ai-Hua JinInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia. a.jin@imb.uq.edu.au.
Sébastien DutertreInstitut des Biomolécules Max Mousseron, Département des acides amines, Peptides et Protéines, Unité Mixte de Recherche 5247, Université Montpellier 2-Centre Nationale de la Recherche Scientifique, Place Eugène Bataillon, 34095 Montpellier CEDEX 5, France. sebastien.dutertre@umontpellier.fr.ORCID 0000-0002-2945-1484
Mriga DuttInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia. m.dutt@uq.edu.au.ORCID 0000-0003-4240-1219
Vincent LavergneLéon Bérard Cancer Center, 28 rue Laennec, 69008 Lyon, France. vincent.lavergne@protonmail.com.
Alun JonesInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia. a.jones@imb.uq.edu.au.
Richard J LewisInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia. r.lewis@imb.uq.edu.au.ORCID 0000-0003-3470-923X
Paul F AlewoodInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia. p.alewood@imb.uq.edu.au.
The University of Queensland · AUCentre de Recherche en Cancérologie de Lyon · FRUniversité de Montpellier · FR

Funding

National Health and Medical Research Council APP1072113
6 · The paper itself

Abstract

Individual variation in animal venom has been linked to geographical location, feeding habit, season, size, and gender. Uniquely, cone snails possess the remarkable ability to change venom composition in response to predatory or defensive stimuli. To date, correlations between the venom gland transcriptome and proteome within and between individual cone snails have not been reported. In this study, we use 454 pyrosequencing and mass spectrometry to decipher the transcriptomes and proteomes of the venom gland and corresponding predation-evoked venom of two specimens of

Indexed as

AnimalsBiological Variation, PopulationBiosynthetic PathwaysChromatography, LiquidComputational BiologyConotoxinsConus SnailDNA, ComplementaryGene Expression ProfilingGene Expression RegulationPredatory BehaviorProteomeProteomicsSequence Analysis, DNASpectrometry, Mass, Electrospray IonizationTranscriptomeConotoxinsDNA, ComplementaryProteome454 sequencingcone snail venomconopeptideconotoxinConus imperialisiTRAQmass spectrometryproteomicstranscriptomicsvenom transcriptome

Identifiers

PMID30893765
PMCPMC6471084
OpenAlexW2921329518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.