Evidence map›Paper›PMID 30893552›Full record

ArticleACS chemical biology2019

Hyperpolarized [6-

Andrew Cho, Roozbeh Eskandari, Kristin L Granlund, Kayvan R Keshari

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. New Horizons in HyperpolarizedMolecular imaging and biology · 2024
    Article
  6. Article
  7. Hyperpolarized [5-Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Biomedical Applications of the Dynamic Nuclear Polarization and Parahydrogen Induced Polarization Techniques for HyperpolarizedMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021
    Review
  12. Review
  13. Imaging Brain Metabolism Using HyperpolarizedTrends in neurosciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew ChoDepartment of Biochemistry and Structural Biology , Weill Cornell Graduate School , New York , New York 10065 , United States.ORCID 0000-0002-5396-5354
Roozbeh EskandariDepartment of Radiology , Memorial Sloan Kettering Cancer Center , New York , New York 10065 , United States.
Kristin L GranlundDepartment of Radiology , Memorial Sloan Kettering Cancer Center , New York , New York 10065 , United States.
Kayvan R KeshariDepartment of Biochemistry and Structural Biology , Weill Cornell Graduate School , New York , New York 10065 , United States.
Memorial Sloan Kettering Cancer Center · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
GE Diamond DNP PolarizerS10OD016422 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2014 to 2014
$600k
Using [6-13C,6-15N3]-L-Arginine for the molecular imaging of in vivo tumor arginase flux, and towards understanding the role of arginase isoforms in cancer metabolism.F30CA225174 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHO, ANDREW · 2018 to 2021
$175k
NCI NIH HHS F30 CA225174NCI NIH HHS P30 CA008748NIGMS NIH HHS T32 GM007739NIH HHS S10 OD016422
6 · The paper itself

Abstract

Alterations in arginase enzyme expression are linked with various diseases and have been shown to support disease progression, thus motivating the development of an imaging probe for this enzymatic target.

Indexed as

ArginaseArginineCarbon IsotopesKineticsMolecular ProbesNitrogen IsotopesArginaseArginineCarbon IsotopesMolecular ProbesNitrogen Isotopes

Identifiers

PMID30893552
PMCPMC6474818
OpenAlexW2923145483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.